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Author Instructions

Book chapters Meltzer PS, Kallioniemi A, Trent JM. Chromosome alterations in human solid tumors. In: Vogelstein
B, Kinzler KW, editors. The genetic basis of human cancer. New York: McGraw-Hill; 2002. pp. 93-
113.
Online resource FDA News Release. FDA approval brings first gene therapy to the United States. Available from:
https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm574058.htm. [Last accessed
on 30 Oct 2017]
Conference proceedings Harnden P, Joffe JK, Jones WG, editors. Germ cell tumours V. Proceedings of the 5th Germ Cell
Tumour Conference; 2001 Sep 13-15; Leeds, UK. New York: Springer; 2002.
Conference paper Christensen S, Oppacher F. An analysis of Koza's computational effort statistic for genetic
programming. In: Foster JA, Lutton E, Miller J, Ryan C, Tettamanzi AG, editors. Genetic
programming. EuroGP 2002: Proceedings of the 5th European Conference on Genetic Programming;
2002 Apr 3-5; Kinsdale, Ireland. Berlin: Springer; 2002. pp. 182-91.
Unpublished material Tian D, Araki H, Stahl E, Bergelson J, Kreitman M. Signature of balancing selection in Arabidopsis.
Proc Natl Acad Sci U S A. Forthcoming 2002.
For other types of references, please refer to U.S. National Library of Medicine.
The journal also recommends that authors prepare references with a bibliography software package, such as EndNote to
avoid typing mistakes and duplicated references.
2.3.3.10 Supplementary Materials
Additional data and information can be uploaded as Supplementary Material to accompany the manuscripts. The Additional
data and information can be uploaded as Supplementary Materials to accompany the manuscripts. The supplementary
materials will also be available to the referees as part of the peer-review process. Any file format is acceptable, such as data
sheet (word, excel, csv, cdx, fasta, pdf or zip files), presentation (powerpoint, pdf or zip files), image (cdx, eps, jpeg, pdf,
png or tiff), table (word, excel, csv or pdf), audio (mp3, wav or wma) or video (avi, divx, flv, mov, mp4, mpeg, mpg or wmv).
All information should be clearly presented. Supplementary materials should be cited in the main text in numeric order
(e.g., Supplementary Figure 1, Supplementary Figure 2, Supplementary Table 1, Supplementary Table 2, etc.). The style of
supplementary figures or tables complies with the same requirements on figures or tables in main text. Videos and audios
should be prepared in English, and limited to a size of 500 MB.

2.4 Manuscript Format
2.4.1 File Format
Manuscript files can be in DOC and DOCX formats and should not be locked or protected.
2.4.2 Length
The word limit is specified in the item “Types of Manuscripts”. There are no restrictions on number of figures or number of
supporting documents. Authors are encouraged to present and discuss their findings concisely.

2.4.3 Language
Manuscripts must be written in English.

2.4.4 Multimedia Files
The journal supports manuscripts with multimedia files. The requirements are listed as follows:
Video or audio files are only acceptable in English. The presentation and introduction should be easy to understand. The
frames should be clear, and the speech speed should be moderate.
A brief overview of the video or audio files should be given in the manuscript text.
The video or audio files should be limited to a size of up to 500 MB.
Please use professional software to produce high-quality video files, to facilitate acceptance and publication along with the
submitted article. Upload the videos in mp4, wmv, or rm format (preferably mp4) and audio files in mp3 or wav format.

2.4.5 Figures
Figures should be cited in numeric order (e.g., Figure 1, Figure 2) and placed after the paragraph where it is first cited;
Figures can be submitted in format of tiff, psd, AI or jpeg, with resolution of 300-600 dpi;
Figure caption is placed under the Figure;
Diagrams with describing words (including, flow chart, coordinate diagram, bar chart, line chart, and scatter diagram, etc.)
should be editable in word, excel or powerpoint format. Non-English information should be avoided;
Labels, numbers, letters, arrows, and symbols in figure should be clear, of uniform size, and contrast with the background;
Symbols, arrows, numbers, or letters used to identify parts of the illustrations must be identified and explained in the
legend;
Internal scale (magnification) should be explained and the staining method in photomicrographs should be identified;
All non-standard abbreviations should be explained in the legend;
Permission for use of copyrighted materials from other sources, including re-published, adapted, modified, or partial