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Conway et al. Vessel Plus 2020;4:25  I  http://dx.doi.org/10.20517/2574-1209.2020.19                                               Page 5 of 11

               Table 1. Demographics of emergency admissions (2011-2018) by hscTnT status
                Factor                   Level            hscTnT -          hscTnT +          P-value
                N                                      40,484             11,730
                Gender                  Male           19,652 (48.5%)     5,836 (49.8%)        0.02
                                        Female         20,832 (51.5%)     5,894 (50.2%)
                Age, median (IQR)                      61.0 (42.2, 76.4)  75.0 (60.2, 83.6)    < 0.001
                Length of stay (days)                  4.6 (2.0, 8.7)     6.6 (3.1, 12.3)      < 0.001
                Outcome                 Alive          39,368 (97.2%)     10,788 (92.0%)       < 0.001
                                        Died           1,116 (2.8%)       942 (8.0%)
                AISS                    1              1,426 (4.2%)       160 (1.5%)           < 0.001
                                        2              2,868 (8.4%)       321 (3.0%)
                                        3              4,852 (14.3%)      559 (5.2%)
                                        4              6,302 (18.6%)      935 (8.7%)
                                        5              7,035 (20.7%)      1,518 (14.2%)
                                        6              11,470 (33.8%)     7,225 (67.4%)
                Sepsis status           1              32,332 (79.9%)     8,591 (73.2%)        < 0.001
                                        2              7,011 (17.3%)      2,701 (23.0%)
                                        3              1,141 (2.8%)       438 (3.7%)
                Co-morbidity score      < 6            23,765 (58.7%)     4,090 (34.9%)        < 0.001
                                        < 10           13,037 (32.2%)     5,121 (43.7%)
                                        < 13           2,793 (6.9%)       1,781 (15.2%)
                                        < 16           648 (1.6%)         485 (4.1%)
                                        < 20           231 (0.6%)         231 (2.0%)
                MDC                     Neuro          7,724 (18.0%)      876 (11.9%)          < 0.001
                                        Resp.          10,417 (24.3%)     2,327 (31.7%)
                                        Cardiac        6,378 (14.9%)      1,796 (24.5%)

               hscTnT: high-sensitivity cardiac troponin; AISS: acute illness severity score; LOS: length of stay; IQR: inter-quartile range; MDC: major
               disease category






































               Figure 1. hscTnT level (ng/L) linearly predicted outcome. The multivariable logistic regression model was adjusted for Acute Illness
               Severity Score, Comorbidity Score, and Sepsis status. Increasing hscTnT level predicted 30-day in-hospital mortality (calculated on per
               admission episode or on unique patient basis) derived from and plotted based on the model prediction. hscTnT: high-sensitivity cardiac
               troponin
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