Page 262 - Read Online

Page 8 of 10 Idhrees et al. Vessel Plus 2020;4:23 I http://dx.doi.org/10.20517/2574-1209.2020.15
[63]
recurrent regurgitation. Matsuura et al. reported that the outcomes of aortic valve replacement (AVR) are
comparable to aortic root replacement, though late dilatation of the residual ascending aorta is the major
concern in long-term follow-up for patients with AVR. Redo-AVR was done in three-fourths of patients
who underwent valve sparing aortic root replacement within 3 years of follow-up after the operation.
Considering these facts, it is advisable to do an aortic root replacement for TA patients than to consider an
AVR or David’s procedure. Aortic root replacement can safely be performed and shows a higher event-free
ratio when compared to AVR alone in TA [47,63,64] .

CONCLUSION
TA is a rare with a challenging course of disease process. Since the incidence is low, there are no formal
guidelines for treatment of these patients. Considering the facts, the treatment has to be individualised
to patients. It is preferred to avoid surgery in the active phase, and if required, disease activity can be
controlled with medications and surgery. Long-term surveillance is required for all these patients as they
are prone to complications.

DECLARATIONS
Authors’ contributions
Contributed equally to the conception, data collection and writing of the manuscript: Idhrees M,
Thilagavathi N, Bashir M, Velayudhan BV

Availability of data and materials
Not applicable.

Financial support and sponsorship
None.

Conflicts of interest
All authors declared that there are no conflicts of interest.

Ethical approval and consent to participate
Not applicable.

Consent for publication
Not applicable.

Copyright
© The Author(s) 2020.

REFERENCES
1. Zaldivar Villon MLF, de la Rocha JAL, Espinoza LR. Takayasu arteritis: recent developments. Curr Rheumatol Rep 2019;21:45.
2. Seyahi E. Takayasu arteritis: an update. Curr Opin Rheumatol 2017;29:51-6.
3. Mohammad AJ, Mandl T. Takayasu arteritis in southern Sweden. J Rheumatol 2015;42:853-8.
4. Gudbrandsson B, Molberg Ø, Garen T, Palm Ø. Prevalence, incidence, and disease characteristics of Takayasu arteritis by ethnic
background: data from a large, population-based cohort resident in Southern Norway. Arthritis Care Res (Hoboken) 2017;69:278-85.
5. Watanabe Y, Miyata T, Tanemoto K. Current clinical features of new patients with Takayasu arteritis observed from cross-country
research in Japan: age and sex specificity. Circulation 2015;132:1701-9.
6. Isobe M, Amano K, Arimura Y, Ishizu A, Ito S, et al. JCS 2017 Guideline on Management of Vasculitis Syndrome - Digest Version. Circ J
2020;84:299-359.
7. Renauer P, Sawalha AH. The genetics of Takayasu arteritis. Presse Med 2017;46:e179-87.
8. Facchinetti M, Pierantonio Ostuni & Gabriella Cardinale. A familial case of Takayasu arteritis: HLA-related genetic susceptibility and