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Genovesi et al. Vessel Plus 2021;5:50 https://dx.doi.org/10.20517/2574-1209.2021.67 Page 9 of 11

given a substantial contribution to the differential diagnosis of this pathology; unfortunately, scintigraphy
with osteophilic radiopharmaceuticals is not able by itself to identify all forms of CA and does not allow
excluding an AL form in the case of concomitant monoclonal gammopathy. In this sense, PET/CT with
specific radiopharmaceuticals for the amyloid substance could represent an additional non-invasive
diagnostic tool, helping to reduce the time required for diagnosis and avoiding the need to use invasive tests
with potential serious complications such as endomyocardial biopsy [Figure 2].

DECLARATIONS
Authors’ contributions
Made substantial contributions to the conception and to the writing of this paper: Genovesi D, Giorgetti A

Availability of data and materials
Not applicable.

Financial support and sponsorship
None.

Conflicts of interest
Both authors declared that there are no conflicts of interest.

Ethical approval and consent to participate
Not applicable.

Consent for publication
Not applicable.

Copyright
© The Author(s) 2021.

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