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Ziai et al. Plast Aesthet Res 2020;7:53 Plastic and
DOI: 10.20517/2347-9264.2020.151 Aesthetic Research

Review Open Access

Periocular rejuvenation using hyaluronic acid fillers

Kasra Ziai , Jessyka G. Lighthall 1,2
1
1 Department of Otolaryngology-Head and Neck Surgery, The Pennsylvania State University, College of Medicine, Hershey, PA
17033, USA.
2 Facial Plastic and Reconstructive Surgery Division, Department of Otolaryngology-Head and Neck Surgery, The Pennsylvania
State University, College of Medicine, Hershey, PA 17033, USA.
Correspondence to: Dr. Jessyka G. Lighthall, Facial Plastic and Reconstructive Surgery Division, Department of Otolaryngology-
Head and Neck Surgery, The Pennsylvania State University, College of Medicine, 500 University Drive, H091, Hershey, PA
17033, USA. E-mail: jlighthall@pennstatehealth.psu.edu
How to cite this article: Ziai K, Lighthall JG. Periocular rejuvenation using hyaluronic acid fillers. Plast Aesthet Res 2020;7:53.
http://dx.doi.org/10.20517/2347-9264.2020.151
Received: 16 Jul 2020 First Decision: 24 Aug 2020 Revised: 27 Aug 2020 Accepted: 14 Sep 2020 Published: 12 Oct 2020

Academic Editor: Wen-Guo Cui Copy Editor: Cai-Hong Wang Production Editor: Jing Yu

Abstract
The eyes and periocular region are critical for emotive display and play a key role in social interactions. This
region includes the upper and lower eyelids, brow-lid complex, and lid-cheek complex. Perturbances in this area
can lead to a prematurely aged appearance and patients complain of emotive misinterpretation. It often shows
the earliest signs of facial aging, leading to a tired, sad, or angry appearance. With the evolution of medical
and surgical knowledge on facial aging, there has been a shift from isolated volume reducing interventions for
periorbital aging to volume replacement techniques. The treatment of periocular aging is multifactorial and
often includes resurfacing, chemodenervation, surgical interventions, and volumization. The minimally-invasive,
office-based nature of fillers has resulted in their increased popularity and filler placement has become one of
the most commonly performed cosmetic oculoplastic interventions. With a multitude of fillers emerging over the
past decade or so, facial plastic surgeons have been equipped with the means to address age-related periorbital
hollowing and skeletonization in an outpatient setting. An appropriate knowledge of periocular anatomy, types
of fillers, proper injection technique, and management of potential complications is required for safe injection
and to achieve optimal aesthetic outcomes. This paper reviews the use of hyaluronic acid fillers for periocular
rejuvenation.

Keywords: Filler, hyaluronic acid, periocular, facial aging

© The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0
International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use,
sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long
as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license,
and indicate if changes were made.

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