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Orgun et al.                                                                                                                                          Regenerative mechanisms of adipose-derived stem cells

















           Figure 4: Patient presented at Figure 3, 2 years after surgery. From left to right: pre-operative frontal view, back view, left lateral view, right
           lateral view

           Table 2: Comparison between extended abdominoplasty   sexual activity,  hygiene, and it  can frequently cause
           technique and traditional torsoplasty              recurrent bouts of infection.
           Characteristics   Extended abdominoplasty Torsoplasty
           Excisedtissue, g          3,430          3,460.9   The post-bariatric  patient represents  a challenge
           Blood loss, mL            628.6          1,085.4   for plastic surgeon.  Although  post-bariatric  body-
           Trasfusion rate, %          0             27.3     contouring procedures are generally  associated with
           Operation lenght          3 h 30 s       4 h 30 s  high rates of patient satisfaction, the surgeon has to face
           Hospitalization time, days  7.8           12.5     the negative impact of postoperative complications.
                                                              The post-bariatric surgery population appears to be at
           Peri and postoperative bleeding led to three cases of   higher risk compared to patients who are not obese. [14]
           anaemia necessitating blood transfusions (14.3%) in
           the second group; no blood transfusion was needed in   Arthurs et al. [15]  found that pre-panniculectomy BMI was
           the first group.                                   the most important factor that independently predicted
                                                              postoperative  complications  after a panniculectomy;
           No other  major  complications occurred during the   meaning  that post-bariatric  surgery  population  is at
           postoperative period in both groups, there was no need   higher risk compared to non-obese patients. Patients
           to drain hematoma or seroma, patients were mobilized   with a BMI greater than 25 kg/m  are at nearly three
                                                                                            2
           during the first postoperative day and were discharged   times the risk of postoperative wound complications.
           without drains.                                    Other important risk factors for complications  are
                                                              nutritional deficiencies, smoking, venous varicosities,
           Only  5  cases  of  superficial  cutaneous  necrosis   and poor quality orinelastic tissues.
           occurred on the bisiliac suture line, 2 in the first group
           and 3 in the second group, solved with local dressings   To obtain the best outcomes, a comprehensive
           in less than 3 weeks.                              perioperative  approach  is required. Proper patient
                                                              selection, carefully considered surgical timing and the
           Patients were uniformly pleased with their results: 90%   choice of  the surgical technique are fundamental to
           of them were very satisfied, whereas 10% graded their   avoid complications.
           results as satisfactory.
                                                              There are many anatomical regions that  massive
           DISCUSSION                                         weight  loss patients would  like corrected: redundant
                                                              flank and abdomen, hip rolls, breasts, arms, buttocks
           The National  Institutes of Health  Consensus      and thigh ptosis. For this reason body contouring  is
           Conference stated in 1991 “only surgery has proven   generally not considered as a single stage procedure.
           effective over the long term for most patients with
           clinically severe obesity”. This statement was confirmed   Among all the body contouring  procedures,
           and updated in 2004, by the  American  Society for   abdominoplasty  has a  crucial role in body image
           Bariatric Surgery (recently renamed as the American   recovery. But the results, even in the most extensive
           Society for Metabolic  and Bariatric Surgery). [13]  The   form of abdominoplasty  are usually  suboptimal
           number of bariatric surgery procedures has increased   because the back and lateral flank deformities are not
           steadily  since  then and, as a result, the number  of   considered.
           massive weight loss patients seeking body-contouring
           procedures has considerably  grown.  The redundant   To address the circumferential nature of  the skin
           excess skin interferes with fitting clothing, physical and   excess in these patients, various surgical techniques
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