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Orgun et al.                                                                                                                                          Regenerative mechanisms of adipose-derived stem cells

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           Figure 1: (A) Anterior pre-operative marking, arrows illustrate the border of the extension of abdominoplasty; (B) the upper flap of
           adipocutaneous excess marked; (C) extension of the incision line dorsally; (D) posterior pre-operative marking, in evidence the pre-sacral
           area non-interested by incision lines
           be marked for the correct alignment of the upper and   is performed with a resorbable suture whenever is
           lower flaps during the suture.                     needed. The navel is externalized, and two additional
                                                              drains  are placed  in  the anterior  trunk.  The surgical
           Surgical technique                                 wound is closed again in three levels, as in the dorsal
           The patient is anaesthetised and then placed in prone   incision.
           position. Pressure sore protections are placed under
           shoulders, knees and ankles. The patient is prepared   Postoperative care
           from  scapula to  buttocks with povidoneiodine.  Skin   All patients received compression stockings and
           and subcutaneous soft  tissues are incised following   daily prophylactic  low-molecular-weight   heparin
           the preoperative markings to the lumbar fascia without   subcutaneously, until 1 week after discharge.  The
           undermining of the non-resected tissues. Haemostasis   patients were mobilized from the first day after surgery.
           is  carefully performed by  electrocautery.  After  the   Antibiotics were administered intravenously during the
           excision of  the  adipocutaneous  tissue,  two drains   surgery  and continuedorally until  discharge.  Drains
           are placed.  Three layer closure is performed: Vicryl   were removed after 4-5 days.
           2/0  (Ethicon Inc,  Somerville,  New Jersey) for  fascia
           superficialis,  Monocryl  3/0  (Ethicon  Inc,  Somerville,   Follow-up
           New Jersey) for the deep dermis and Monocryl 4/0 for   The patients were discharged  after a few days and
           endodermic suture.                                 followed up at 15 days, 1, 2, 3 and 6 months and 1 year,
                                                              or more frequently in the presence of complications.
           Then the patient is placed in the supine position;
           skin and subcutaneous  tissues are incised  down   RESULTS
           to  the anterior  abdominal  wall fascia respecting the
           preoperative  markings. Umbilicus is isolated and   We performed the extended abdominoplasty technique
           preserved and the flap is elevated to the chest and the   on 21 post-bariatric patients from September 2014 to
           xiphoid area. Adipocutaneous excess is removed by a   November  2015  and  circumferential  abdominoplasty
           flute mouthpiece incision from the subcutaneous tissue   or torsoplasty on 21 postbariatric patients during the
           to the superficial fascia. Plication of the muscular fascia   same period.

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