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Omranipour et al.                                                                                                                                                                Ipsilateral or contralateral TRAM flap

            pedicle TRAM patients and in 34.8% of the contralateral group (P < 0.001). Total early hospital stay was longer in contralateral
            pedicle TRAM flaps (7.66 days vs. 10.68 days, P = 0.83). Higher complications were encountered in contralateral pedicle TRAM
            flaps compared to ipsilateral pedicle TRAM patients (39.1% vs. 19.5%, P = 0.001). The type of pedicled TRAM flap (ipsilateral vs.
            contralateral), had significant effect on complications (odds ratio =  0.007, P = 0.002) while other variables had no significant effect on
            the incidence of complications. Conclusion: This study indicates that the overall outcome and mid-term morbidity-free survivals of
            ipsilateral pedicle TRAM flap breast reconstruction are statistically superior to contralateral pedicle TRAM flap breast reconstruction.
            Both of these procedures are reasonably feasible and safe. These findings lead us to discourage the use of contralateral pedicle TRAM
            flap when an ipsilateral option is feasible.


           INTRODUCTION                                       reduce the blood supply of the flap [7,8] . In order to
                                                              avoid the folding and the vascular flow surgeons have
           Breast reconstruction has several beneficial effects on   preferred to use the contralateral pedicle TRAM flap.
           the psychosocial well-being and quality of life. Different   The contralateral pedicle TRAM flap also seemed
           studies have shown that breast reconstruction      to have some aesthetic limitations due to ablation of
           improves self-image, sexuality, and decreased rates   the xiphoid subunits and the medial infra-mammary
                                                         [1]
           of depression in women who have had mastectomy .   fold. There  are  also  some  limitations  from  the
           Additionally, patients who undergone reconstruction   shorter pedicle length . There are reports indicating
                                                                                  [7]
           with autologous tissue, in comparison with those who   differences in early and long-term outcome of these
           have undergone reconstruction with tissue expanders/  two techniques . Some authors reported similar
                                                                             [9]
           implants, have better long-term quality of life .  safety of both techniques [10]  while others favored one
                                                  [2]
                                                              pedicle TRAM technique over the other one [8,9] .
           Transverse rectus abdominis myocutaneous (TRAM)
           techniques have long been applied but selecting a   Our objective was to retrospectively compare
           superior technique is controversial. The selection of   outcomes of ipsilateral and contralateral pedicle TRAM
           the best procedure significantly affects the outcome   flaps in a retrospective cohort study. In our center
           of flap viability, patients’ satisfaction, and quality of   free flaps for breast reconstruction are not routinely
           life . The pedicle TRAM flap is still one of the most   performed. Therefore we performed this study to
              [3]
           common procedure performed in many centers.        analyze the outcomes and complications of TRAM
           Our study demonstrates that it is associated with   flaps performed in our center. We were able to assess
           a low complication rate and a high level of patient   the risk factors which could cause more post-operative
                                 [4]
           satisfaction in our center .                       complications and compare the results of ipsilateral
                                                              and contralateral TRAM flaps retrospectively. We
           Morbidity and adverse events following different   are aware that free flaps will substitute TRAM flaps
           reconstructive breast surgeries are reported to be   inevitably, so in this study we measured the results of
           widely varied. In general, patients selected for pedicle   TRAM flaps in our center. The study primary endpoints
           TRAM flap reconstruction must have adequate        were postoperative morbidity (defined as occurrence
           abdominal soft tissue  for  the  procedure to be   of at least one of the postoperative complications
           successful. There are several identified risk factors   within the follow-up period), need for re-hospitalization
           contributing to the post operative complications of   and need for re-operation.
           pedicle TRAM flap reconstruction. These factors
           are cigarette smoking, obesity, prior radiation    METHODS
           therapy, abdominal surgery, and significant medical
                       [5]
           comorbidities .                                    In total of 110 patients who underwent unilateral breast
                                                              reconstruction with pedicle TRAM flap at the Cancer
           As the experience and comfort with micro-surgical   Institute of Tehran University of Medical sciences
           techniques and instrumentation and post-op         from January 1996 to June 2011, were included in
           monitoring facilities are not available in all centers.   this study. The ethics committee accepted this study
           Surgeons perform the pedicle TRAM flap because it   and the patients were informed about it during their
           demands less technical and facility requirements and   follow-up exams. Patients with micro-vascular super-
           has fewer complete flap loss in comparison with free   charging of the flap or those who received a bi-pedicle
                         [6]
           flap techniques .                                  or bilateral TRAM flap were excluded. Patients’ age,
                                                              height, weight, history of smoking, and associated
           Rotation of pedicle TRAM flap can be ipsilateral   comorbidities (diabetes mellitus, dyslipidemia and
           or contralateral. Some surgeons believe that the   hypertension), steroid use, history of liposuction, tumor
           ipsilateral procedure might result in more tension on   staging (based on TNM criteria), presence of tumor
           the vascular pedicle and folding of the pedicle could   markers (estrogen receptor status, progesterone
            156                                                                                    Plastic and Aesthetic Research ¦ Volume 4 ¦ September 29, 2017
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