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Zhu et al.                                                                                                                                                                              Modified Robertson vs. Wise pattern

            Table 1: Demographic statistics                   Table 3: Late postoperative period
                        ROB (range)    WISE (range)  P value                ROB (range)   WISE (range)  P value
            Age (years)  36.9 (30-41)  38.5 (21-65)   0.74    SNtoNIP (cm)  24.4 (21.4-26.4)  24.1  (21.5-26.4)  0.57
            BMI (kg/m )  33.9 (31.1-37.2)  30.9 (26.4-35.7)  0.08
                   2
            Total breast   809 (459-1,080)  729 (555-1,253)  0.26  NIPtoIMF (cm)  13.2 (10.3-15.9)  10.8  (8.3-14.2)  0.00*
            volume (mL)                                       NIPtoNIP (cm)  24.8 (22.5-27.6)  21.3  (17.3-23.6)  0.00*
            Tissue                                            NipProj (cm)  6.59 (3.18-9.00)  6.70  (4.65-9.18)  0.83
            resected (mL)  695 (406-1,000)  712 (449-1,280)  0.84
                                                              MaxProj (cm)  5.52 (4.08-7.46)  6.54  (4.50-8.77)  0.01*
                                                                        2
           Table 2: Early postoperative period                AreolaSA (cm )  26.9 (16.3-37.1)  21.6  (12.9-33.7)  0.02*
                                                                        2
                         ROB (range)   WISE (range)  P value  BreastSA (cm )  494  (402-593)  419  (344-559)  0.00*
           SNtoNIP (cm)  23.1 (20.1-25.3)  23.7 (20.9-25.6)  0.24  TotVol (mL)  856  (486-1,183)  709  (489-1,123)  0.06
           NIPtoIMF (cm)  12.3 (9.3-15.3)  10.6 (8.4-12.9)  0.00*  SupPole%  62.9 (51.1-73.6)  58.3  (42.3-69.9)  0.05*
           NIPtoNIP (cm)  23.6 (15.5-27.7)  21.6 (17.0-24.6)  0.17  MedPole%  29.6 (20.3-42.1)  46.9  (34.2-62.9)  0.00*
           NipProj (cm)  5.91 (2.15-8.70)  6.97 (5.09-9.26)  0.10  *Statistically significant
           MaxProj (cm)  5.55 (4.09-8.64)  6.69 (4.67-9.26)  0.01*  tissue resected (695 g ROB vs. 712 g WISE, P = 0.84;
           AreolaSA (cm )  23.8 (21.3-28.1)  19.0 (13.17-24.05)  0.00*  Table 1). Complications requiring surgical revision were
                     2
           BreastSA (cm )  490 (388-571)  422 (355-547)  0.00*  minimal (Fisher’s exact test: 2/14 ROB vs. 0/24 WISE,
                     2
           TotVol (mL)  809 (459-1,081)  729 (555-1,253)  0.26  P = 0.13). The 2 complications were both dog-ears that
           SupPole%     59.6 (45.7-69.4)  56.9 (44.2-66.6)  0.21  developed at the late postoperative period and revised
           MedPole%     27.0 (20.5-50.2)  45.5 (31.2-63.1)  0.00*  under local anesthesia. Preoperative 3D photographs
           *Statistically significant                         were not taken or analyzed due to the limitations of the
                                                              software to accurately measure massive breasts with
           by total breast volume. Percent medial pole volume was   ptosis resting on the abdominal wall.
           defined as volume of the breast medial to a XZ sagittal
           plane through the point of maximum projection divided   Early postoperative period
           by total breast volume.                            In the early postoperative period [Table 2], sternal notch
                                                              to nipple distance was not significantly different between
           Statistical  analysis  was  completed  using  Statistical   the 2 cohorts (23.1 cm ROB vs. 23.7 cm WISE, P =
           Package for the Social Sciences. Independent samples   0.24); however, nipple to IMF was significantly greater
           t-tests  and  chi-squared  tests  (Fischer’s  exact)  were   in  the  modified  Robertson  cohort  (12.3  cm  ROB  vs.
           used where appropriate and a P ≤ 0.05 was considered   10.6 cm WISE, P < 0.01). Internipple distance was not
           statistically  significant.  With  an  estimated  3%  effect   significantly different between the 2 cohorts (23.6 cm
           size  in  the  modified  Robertson  group  and  6%  in  the   ROB vs. 21.6 cm WISE, P = 0.17). Nipple projection was
           inferior pedicle group for tissue movement to the inferior   not significantly different between the 2 cohorts (5.91 cm
           pole, a common standard deviation of 2, a 0.5 level of   ROB vs. 6.97 cm WISE, P = 0.10); however, maximum
           significance,  and  a  0.8  power  level,  the  sample  size   breast projection was greater in the Wise cohort (5.55
           was calculated to be 7 in each cohort.             cm ROB vs. 6.69 cm WISE, P = 0.01). Areola surface
                                                              area was greater in the modified Robertson cohort (23.6
           RESULTS                                            cm  ROB vs. 19.0 cm  WISE, P < 0.01).
                                                                                 2
                                                                 2
           Twenty-two patients consented and completed the    Total  breast  volume  was  not  significantly  different
           required components of the study. Two patients were   between the two cohorts (809 mL ROB  vs. 729 mL
           excluded as outliers due to excessive BMI and excessive   WISE, P = 0.26). Percent volume in the superior pole
           volumes resected, and 1 patient was excluded due to   was not different between the 2 cohorts (59.6% ROB
           low BMI. In total, there were 14 measured breasts in the   vs. 56.9% WISE, P = 0.21); however, percent volume in
           modified Robertson cohort (ROB) and 24 breasts in the   the medial pole was greater in the WISE cohort (27.0%
           Wise cohort (WISE).                                ROB vs. 45.5% WISE, P < 0.01).

           No  statistically  significant  differences  were  found   Late postoperative period
           between the 2 cohorts regarding age (36.9 years ROB   In the late postoperative  period  [Table 3, Figure 1],
           vs. 38.5 years WISE, P = 0.74), BMI (33.9 kg/m  ROB vs.   sternal notch to nipple distance was not significantly
                                                   2
           30.9 kg/m  WISE, P = 0.08), total breast volume (809 mL   different between the 2 cohorts (24.4 cm ROB vs. 24.1 cm
                    2
           ROB vs. 729 mL WISE, P = 0.26), or the weight of breast   WISE,  P = 0.57); however,  nipple  to IMF  remained
            286                                                                                    Plastic and Aesthetic Research ¦ Volume 3 ¦ September 20, 2016
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