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Original Article                                    Plastic and Aesthetic Research





           Blood lipid profiles following nonfocused


           ultrasonic treatment for noninvasive body

           contouring





           Takashi Honda , Katsuhiro Kure , Hiroyuki Goto , Takuya Suzuki , Mariko Mogami ,
                                                                                    2
                                                                                                       3
                                                                 1
                                               1
                            1
           Tsukasa Isago   3
           1 Department of Plastic and Aesthetic Surgery, Tokyo Women’s Medical University, Medical Center East, Tokyo 116-0013, Japan.
           2 Clinical laboratory, Tokyo Women’s Medical University, Medical Center East, Tokyo 116-0013, Japan.
           3 Department of Plastic and Reconstructive Surgery, Tokyo Women’s Medical University, Medical Center East, Tokyo 116-0013, Japan.
           Address for correspondence: Dr. Takashi Honda, Department of Plastic and Aesthetic Surgery, Tokyo Women’s Medical University, Medical
           Center East, 2-20-1 Nishinippori Arakawa-ku, Tokyo 116-0013, Japan. E-mail: honda.takashi@twmu.ac.jp

                           Dr. Takashi Honda is Associate Professor in the Department of Plastic and  Aesthetic Surgery at
                           Tokyo Womens’ Medical University, Medical Center East. His field of expertise includes facial
                           cosmetic surgery, maxillofacial reconstruction, aesthetic laser therapy, and breast surgery including
                           augmentation, reduction and reconstruction.



                ABSTRACT
                Aim: Blood lipid profiles changed following nonfocused ultrasound treatments for body contouring.
                The present study elucidates clinical effects of these devices on adipose tissue. Methods: Ultrasound
                treatments for 5 males and 5 females in a supine position, ages 37-67 years, were applied at 20 KHz
                and 3.0 W/cm  in modulated emission. Whole abdomen was treated by an ultrasound handpiece for
                             2
                30 min followed by a 6-min lymphatic drainage. Waist circumferences at the level of the umbilicus and
                body weight were measured before and immediately after treatment. Blood lipid profiles including
                total cholesterol, low-density lipoprotein, high-density lipoprotein, triglyceride (TG), nonesterified
                fatty acid (NEFA) and lipoprotein-a were measured at baseline, every 10 min during treatment, and
                15, 30, 45, 60, 75, and 90 min after treatment completion. Results: NEFA showed statistically higher
                values  after 10 min following treatment initiation. Subsequent values  remained  high despite  some
                fluctuation, reaching a maximum at 90 min. In contrast, TG gradually decreased in concentration until
                the last measurement, especially for the first 30 min, with statistically significant reduction. Changes in
                other lipid profiles and lipoprotein-a were not significant. Conclusion: Changes in NEFA concentration
                were significant following ultrasound treatment, and suggest that metabolism of TGs stored within the
                adipocytes occurred immediately after treatment initiation.

                Key words:
                Noninvasive body contouring; MC1 device; nonfocused ultrasound; cavitation; blood lipid profiles


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                                    http://parjournal.net       How to cite this article:  Honda T, Kure K, Goto H, Suzuki T,
                                                                Mogami  M,  Isago  T.  Blood  lipid  profiles  following  nonfocused
                                                                ultrasonic treatment for noninvasive body contouring. Plast Aesthet
                                    DOI:                        Res 2016;3:107-10.
                                    10.20517/2347-9264.2015.61
                                                                Received: 28-05-2015; Accepted: 30-12-2015
           © 2016 Plastic and Aesthetic Research | Published by OAE Publishing Inc.                           107
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