Page 65 - Read Online
P. 65
In relation to prescription patterns, there was over the counter without prescription. [9‑11,13] The role
some variability in the preference for perioperative of steroids, especially dexamethasone, as adjuncts in
regimens versus postoperative prescription only. The postoperative pain management has also been reviewed.
role of a preoperative or loading dose of analgesic NSAIDs are also associated with side effects such as GI
medication before surgery has been recommended as bleeding and allergic reactions, and it is critical that these
a form of preemptive analgesia. [19,26] In our study, only drugs be prescribed cautiously. [19,24,25]
35.5% (n = 118) of our participants who preferred the Our study illustrates that the current trend of prescription
peri‑operative regimen gave due consideration to this of analgesic and anti‑inflammatory drugs for routine oral
method of analgesic prescription. implant surgery among Indian dentists is in accordance
The duration of prescription ranged from a self‑medication with the guidelines for management of dental pain
preference or "stat‑on‑symptoms" approach to the worldwide. However, evidence of prescription of drugs
medication being prescribed for 2 to 9 days post‑surgically. not primarily indicated for dental pain management and
Most authors recommend prescription duration of 4 to protocols not consistent with current recommendations,
6 days, and most of our study participants also fell into is noteworthy. It is essential that, to ensure safe delivery
this range. [16,27] All dentists in our study recommended the and avoidance of potential complications arising due to
oral route of delivery, while only a few used an additional these drugs, dental practitioners should be more aware
injection of NSAID drugs. Again, most authors recommend of the appropriate dose, dosage regimen and indications
only oral NSAID therapy for dental and postoperative for specific analgesics. Additionally, further research
pain. [16,27] is required to assess the outcomes, including adverse
effects, related to the prescription of these drugs for oral
When considering the method of prescription, it was seen implant surgery.
that fewer dentists wrote the brand names of the drugs
prescribed. The majority preferred to use generic names REFERENCES
of commercially available drugs, including pre‑formulated
drug combinations. 1. Becker DE, Phero JC. Drug therapy in dental practice: nonopioid and opioid
To manage NSAIDs associated adverse effects on the GI 2. analgesics. Anesth Prog 2005;52:140‑9.
Becker DE. Pain management: Part 1: managing acute and postoperative
tract, a proton pump inhibitor or H2 receptor antagonist dental pain. Anesth Prog 2010;57:67‑79.
is usually recommended for patients that are at high risk 3. Singh G, Ramey DR, Morfeld D, Shi H, Hatoum HT, Fries JF. Gastrointestinal
[10]
of ulcers. Only five of our study participants mentioned tract complications of nonsteroidal anti‑inflammatory drug treatment in
these drugs in their prescriptions. Our study also rheumatoid arthritis. A prospective observational cohort study. Arch Intern
illustrated that only a minority prescribed semi‑synthetic 4. Med 1996;156:1530‑6.
Ong KS, Seymour RA. Maximizing the safety of non‑steroidal anti‑inflammatory
opioid analgesics (tramadol and dextropropoxyphene) and drug use for postoperative dental pain: an evidence‑based approach. Anesth
this trend was also in accordance with indications for use Prog 2003;50:62‑74.
of NSAIDs for dental and post‑surgical pain. [2,16] 5. Turan A, Sessler DI. Steroids to ameliorate postoperative pain. Anesthesiology
2001;15:457‑9.
The role of glucocorticoids as adjuncts for pain and 6. Brodala N. Flapless surgery and its effect on dental implant outcomes. Int J
edema has received interest in recent time. Literature Oral Maxillofac Implants 2009;24:118‑25.
[28]
has shown that the short‑term use of corticosteroids 7. Raffa RB. Pharmacology of oral combination analgesics: rational therapy for
pain. J Clin Pharm Therap 2001;26:257‑64.
is safe and provides analgesia in acute postoperative 8. Datta R, Grewal Y, Batth JS, Singh A. Current trend of antimicrobial
pain in healthy adults. However, the optimal dose, prescription for oral implant surgery among dentists in India. J Maxillofac
[29]
mode and timing of administration remain unclear. Oral Surg 2013;DOI: 10.1007/s12663‑013‑0567‑7.
[30]
One meta‑analysis has provided reliable evidence that 9. Şermet S, Akgün MA, Atamer‑Şimşek S. Analgesic prescription pattern in
the management of dental pain among dentists in İstanbul. Marmara Pharm
dexamethasone is an ideal drug for ameliorating acute J 2012;16:41‑7.
[5]
postoperative pain. Of the 30% of our study sample 10. Mahadi HM, Jamiur RK, Binte WT, Sharmin CS. Study on the use pattern
that did prescribe steroids, the majority did prescribe of NSAIDS in some general and specialized hospitals of Bangladesh. Int Res
J Pharm 2012;3:152‑5.
dexamethasone, but the duration, mode of delivery and 11. Jayanthi MK, Suresha RN. A study of prescribing patterns of NSAIDS in dental
protocol were variable. It is noteworthy that many of the OPD of a tertiary care teaching hospital. Asian J Med Clin Sci 2013;2:27‑9.
dentists in our study prescribed injectable steroid therapy 12. Barasch A, Safford MM, McNeal SF, Robinson M, Grant VS, Gilbert GH.
for up to seven days postoperatively. Patterns of post‑operative pain medication prescribing after invasive dental
procedures. Spec Care Dentist 2011;31:53‑7.
It was interesting to note that pre‑formulated commercially 13. Abbott FV, Fraser MI. Use and abuse of over‑the‑counter analgesic agents.
available drug combinations contained additional drugs J Psychiatry Neurosci 1998;23:13‑34.
such as serratiopeptidase and chlorzoxazone. The role 14. Scottish dental clinical effectiveness programme. Drug prescribing for
dentistry: a clinical guidance. 2nd ed. 2011. p. 51‑63. Available from: http://
of a muscle relaxant in dental implant surgery remains www.sdcep.org.uk/index.aspx?o=2334. [Last accessed on 2015 Feb 02].
unclear. 15. Ong CK, Lirk P, Tan CH, Seymour RA. An evidence‑based update on
non‑steroidal anti‑inflammatory drugs. Clin Med Res 2007;5:19‑34.
Review of current literature reveals that almost all authors 16. Pozzi A, Gallelli L. Pain management for dentists: the role of ibuprofen.
are in favour of the use of conventional NSAIDs, specifically AnnStomatol 2011;2:3‑24.
ibuprofen, ibuprofen with paracetamol and diclofenac, 17. Bhaskar H, Kapoor P, Ragini. Comparison of transdermal diclofenac patch
for the management of dental and postoperative pain with oral diclofenac as an analgesic modality following multiple premolar
extractions in orthodontic patients: a cross over efficacy trial. Contemp Clin
and inflammation. These drugs are also easily available Dent 2010;1:158‑63.
54 Plast Aesthet Res || Vol 2 || Issue 2 || Mar 13, 2015