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Page 6 of 12             Pandey et al. Plast Aesthet Res 2021;8:47  https://dx.doi.org/10.20517/2347-9264.2021.61









































                Figure 4. A variety of anastomotic configurations (named in a lymphatic-to-vein convention) are available to maximize anterograde
                drainage. (A) Single end-to-end anastomosis, (B) end-to-end anastomosis of two lymphatics to two venous branches, (C) end-to-side
                anastomosis, (D) depicts multiple small-caliber, fibrotic (non-translucent) lymphatic vessels and a single, large-caliber vein, for which
                (E) an invaginating “octopus” technique is most appropriate. L: Lymphatic; V: venule.

                                   [64]
               before declaring failure . It can be promoted by massaging distal to incision. Leakproof anastomosis is
               essential to allow lymphatic pressure to build up and overcome the venous pressure . If the microscope is
                                                                                      [65]
                                                                                                      [65]
               equipped with an ICG module, patency can be confirmed by observing ICG flow into the veins . If
               backflow of blood into the lymphatic vessel is observed, venous pressure has exceeded lymphatic pressure,
               and the anastomosis is at risk of thrombosis.

                                                                [31]
               Controversy exists regarding the optimal number of LVAs . Theoretically, a few high-quality anastomoses
               (antegrade flow anticipated) should suffice, but reality often necessitates a quantity-over-quality approach.
               In keeping with this, the senior author (Chen WF) has demonstrated considerable clinical success when
               using suboptimal vessels by creating 8 to 15 LVAs per case [48,54,64] . The following are used as the procedure
               endpoints: (1) six hours of operative time; for experienced microsurgeons, continuing beyond this duration
               typically yields diminishing returns; (2) three consecutive negative incisions (i.e., no suitable lymphatics
               found when proceeding in a distal-to-proximal fashion); or (3) substantial drainage through LVAs causing
               visible limb decompression on the table .
                                                [54]

               Frequently refreshing supermicrosurgical skills on practice models can shorten the learning curve for LVA
               in budding lymphedema surgeons .
                                            [66]
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