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Bon Betemps et al. Plast Aesthet Res 2018;5:19 Plastic and
DOI: 10.20517/2347-9264.2018.24 Aesthetic Research

Original Article Open Access

Projection capacity assessment of hyaluronic acid
fillers

Jérémie Bon Betemps , Francesco Marchetti , Tingsong Lim , Basste Hadjab , Patrick Micheels , Denis
4
1
3
2
1
Salomon , Samuel Gavard Molliard 1
5
1 Research and Development Department, Kylane Laboratoires S.A., Plan-les-Ouates 1228, Switzerland.
2 Surgeon Roma Plastic Surgery Center Private Practice, Roma 00199, Italy.
3 Clique Clinic Private Practice, Petaling Jaya 46300, Malaysia.
4 Dr. Patrick Micheels Private Practice, Genève 1206, Switzerland.
5 Clinique Internationale de Dermatologie Genève S.A. Private Practice, Genève 1201, Switzerland.
Correspondence to: Dr. Samuel Gavard Molliard, Research and Development Department, Kylane Laboratoires S.A., Plan-les-
Ouates 1228, Switzerland. E-mail: samuel.gavard@yahoo.fr
How to cite this article: Bon Betemps J, Marchetti F, Lim T, Hadjab B, Micheels P, Salomon D, Gavard Molliard S. Projection
capacity assessment of hyaluronic acid fillers. Plast Aesthet Res 2018;5:19. http://dx.doi.org/10.20517/2347-9264.2018.24
Received: 17 Apr 2018 First Decision: 18 May 2018 Revised: 11 Jun 2018 Accepted: 11 Jun 2018 Published: 28 Jun 2018

Science Editor: Raúl González-García Copy Editor: Jun-Yao Li Production Editor: Cai-Hong Wang

Abstract

Aim: Hyaluronic acid (HA) is considered as the gold standard biomaterial for facial soft tissue correction. Over the last
8 years, there has been a strong demand from physicians for HA products with high projection capacity to restore facial
volume loss at the level of the cheeks, cheekbones, chin, temples and jawlines. The projection capacity is thus an essential
property for HA fillers especially for the products dedicated to the restoration of the volume of the face.

Methods: In this publication, a new skin model assay for evaluating the projection capacity of HA fillers is presented,
applied and discussed.

Results: This skin model assay enables to efficiently assess the projection capacity of a HA filler product. The comparative
evaluation of a product benefiting from the novel OXIFREE technology and Juvéderm Voluma shows a higher projection
capacity for the OXIFREE product than for Juvéderm Voluma.

Conclusion: This assay is demonstrated to be a key tool to guide physicians in the selection of products with high ability of
tissue projection to optimize their aesthetic outcomes when they need to create facial volume.

Keywords: Hyaluronic acid fillers, projection capacity, skin model assay, facial volume

© The Author(s) 2018. Open Access This article is licensed under a Creative Commons Attribution 4.0
International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use,
sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long
as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license,
and indicate if changes were made.

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