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Page 6 of 8 Bon Betemps et al. Plast Aesthet Res 2018;5:19 I http://dx.doi.org/10.20517/2347-9264.2018.24

A Projection force
80
Normal force F N of compression at 0.9 mm -1 (cN) 60
70

50
40

30
20

0 10
Gel D Juvéderm Voluma
B

Projection height

Gel D Juvéderm Voluma

C Projection height

2.60

2.40

Projection height (mm) 2.00
2.20

1.80

1.60

1.40
Gel D Juvéderm Voluma
Figure 2. Rheological properties and projection heights of two HA volumizers. A: graph of projection forces for the 2 HA gels; B: picture of
the projection heights with the 2 HA gels; C: graph of the projection heights for the 2 HA gels

In conclusion, volumizing products play an increasingly important role in the minimally invasive aesthetic
procedures and they significantly contribute to the growth of the HA filler market on the world scale. HA
volumizers have been demonstrated to be the gold standard solution to restore facial volume loss, especially
for the correction of the midface with key clinical indications for the rejuvenation of the face such as the
treatment of the cheeks, cheekbones, chin and jawlines.

Rheological characteristics analysis was demonstrated to be very useful for the physicians in order to guide
them in the selection and usage of the most relevant products, administration techniques and depths of
injection for the intended treatment.