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Bon Betemps et al. Plast Aesthet Res 2018;5:19  I  http://dx.doi.org/10.20517/2347-9264.2018.24                                Page 7 of 8

               This publication presents a new skin model assay to evaluate the projection capacity of HA fillers. This skin
               model assay was proven to be reliable and reproducible with two HA volumizers, including the market
               leader Juvéderm Voluma. It allows easy highlight of the ability of a HA filler to project the tissue and to
               create volume. It also enables a comparison of the projection capacity levels of different volumizing HA
               products. This model is therefore considered as a new key tool, complementary to the rheological property
               of projection force F , to assess the projection capacity of the HA fillers.
                                N
               The additional acquired knowledge obtained with this new skin model assay contributes to a better
               characterization of the HA fillers which could be selected and used by the physicians for optimizing their
               aesthetic outcomes, as well as patient safety and satisfaction.


               DECLARATIONS
               Authors’ contributions
               Design of the concept and writing of the article: all authors
               Obtaining all the experimental data: Bon Betemps J, Gavard Molliard S


               Availability of data and materials
               Data in this study were derived from searches of the PubMed database. Experimental data were obtained by
               Kylane Laboratoires S.A.


               Financial support and sponsorship
               Kylane Laboratoires S.A. provided the logistical and financial support for the execution of this study.


               Conflicts of interest
               Mr. Samuel Gavard Molliard is employed by Kylane Laboratoires S.A., Mr. Basste Hadjab and Mr. Jérémie
               Bon Betemps serve as consultant of Kylane Laboratoires S.A.


               Ethical approval and consent to participate
               Not applicable.


               Consent for publication
               Not applicable.


               Copyright
               © The Author(s) 2018.



               REFERENCES
               1.   Bui P, Pons Guiraud A, Lepage C. Benefits of volumetric to facial rejuvenation. Part 2: Dermal fillers. Ann Chir Plast Esthet
                   2017;62:550-9. (in French)
               2.   American Society of Plastic Surgeons. 2016 Plastic Surgery Statistics Report. Avaiable from: https://www.plasticsurgery.org/news/
                   plastic-surgery-statistics?sub=2016+Plastic+Surgery+Statistics [Last accessed on 26 Jun 2018]
               3.   De Maio M, DeBoulle K, Braz A, Rohrich RJ; Alliance for the Future of Aesthetics Consensus Committee. Facial assessment and
                   injection guide for botulinum toxin and injectable hyaluronic acid fillers: focus on the midface. Plast Reconstr Surg 2017;140:e540-50.
               4.   Goodman GJ, Swift A, Remington BK. Current concepts in the use of Voluma, Volift and Volbella. Plast Reconstr Surg 2015;136:S139-48.
               5.   Sundaram H, Rohrich RJ, Liew S, Sattler G, Talarico S, Trévidic P, Molliard SG. Cohesivity of hyaluronic acid fillers: development
                   and clinical implications of a novel assay, pilot validation with a five-point grading scale, and evaluation of six U.S. Food and Drug
                   Administration-approved fillers. Plast Reconstr Surg 2015;136:678-86.
               6.   Tran C, Carraux P, Micheels P, Kaya G, Salomon D. In vivo bio-integration of three hyaluronic acid fillers in human skin: a histological
                   study. Dermatology 2014;228:47-54.
               7.   Sundaram H, Cassuto D. Biophysical characteristics of hyaluronic acid soft-tissue fillers and their relevance to aesthetic applications.
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