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Allam et al. Plast Aesthet Res 2024;11:19  https://dx.doi.org/10.20517/2347-9264.2024.21  Page 3 of 16


































                          Figure 1. Framework of application of technological advancements in autologous breast reconstruction.

               3D printing
               While various preoperative techniques like CTA, MRA, and Doppler ultrasound are available for flap
                                                                                            [9]
               perforator mapping, CTA with 3D reconstruction remains the most commonly used . Preoperative
               imaging has the advantage of meticulous perforator selection prior to incision, which can reduce flap
               harvesting and operative times while lowering complication rates. However, the utility of CTA 3D
                                                                                                        [9]
               reconstructed imaging is somewhat limited as it is typically visualized on a two-dimensional monitor .
               Recent advancements aim to address this limitation by enhancing the visualization of perforators in
               three-dimensional space.


               Patient-specific 3D-printed models have shown potential in improving visuo-spatial understanding of flap
               anatomy. A study by DeFazio et al. compared 3D-printed models [Figure 2A] and interpretations of CTA
               imaging against operative findings. 3D-printed models accurately matched intraoperative findings in
               perforator number, source vessel origin, and branching patterns, while CTA interpretations were less
                      [9]
               accurate . The precision of 3D-printed models, with a marginal error averaging less than 1 mm compared
               to over 8 mm in CTA, led to a 20 min reduction in flap harvesting time . Another prospective study
                                                                                [9]
               assessed the use of 3D-printed flap templates in DIEP and MS-TRAM flap breast reconstructions. These
               templates, designed with perforator location indicators, proved as accurate as conventional methods, and
               significantly reduced intraoperative perforator identification time by over 7 min .
                                                                                  [11]

               In a retrospective study, Ogunleye et al. compared 3D-printed models with CTA scans for preoperative
               planning, reinforcing the notion that 3D models can shorten harvesting time and decrease intraoperative
               adjustments . While no significant differences in clinical outcomes were detected due to inadequate power,
                         [10]
                                                                                   [10]
               reconstructions using 3D-printed models showed lower rates of flap take-back . However, the impact of
               3D-printed flap models on clinical outcomes is not well-documented and may be subject to bias due to the
               challenges in conducting blinded studies.
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