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Bansberg et al. Plast Aesthet Res 2024;11:12  https://dx.doi.org/10.20517/2347-9264.2023.109  Page 7 of 13

               Despite substantial experience in closing perforations, attempted repair remains challenging when prior
               septal surgery has been performed regardless of the perforation size. Septal scarring due to one or more
               prior procedures can substantially impact the ability to develop surgical planes for intact mucosal elevation.
               The removal of bone and cartilage during septal surgery results in densely adherent and attenuated mucosa
               that can extend for a distance beyond the perforation margin. A slow and tedious dissection is common for
               perforations resulting from prior septal surgery. This condition is most problematic posteriorly, where a
               thin margin of fused mucosa can pose a substantial challenge to intact bilateral separation before reaching
               cartilage or bone located 1 cm or more posterior to the perforation mucosal margin [Figure 4]. Intact
               elevation of right and left mucosa is facilitated by the injection of saline or local anesthetic to widen the
               margin sharp separation with a #15 blade. The eight patients in this study for whom an interposition graft
               was not placed had prior septal surgery. Operative note review described the substantial difficulty in
               elevating mucosa intact in all patients, resulting in a tenuous single-layer repair that prevented the
               “interposing” of a tissue graft. The difference in perforation sizes for failed repairs between surgical and
               non-surgical etiologies noted in this study was significant. These clinical observations and measurement
               analysis findings support our impression that prior septal surgery increases the technical difficulty
               associated with flap closure procedures, irrespective of perforation size. The difference in failure rates
               between surgical and non-surgical (5.7 vs. 4.7%) etiologies found in this study was not significant and may,
               in part, reflect surgical experience.

               Complete tension-free closure on at least one side is a prerequisite for consistent success in perforation
               surgery utilizing mucosal flaps. The perforation repair procedure presented emphasizes complete coverage
               of the septal defect on the left side through the development and advancement of a superior bipedicled flap
               and, when necessary, an inferior bipedicled flap. The elliptical shape noted for most perforations conforms
               to a repair utilizing superior and inferior longitudinally oriented flaps. Flap incision placement and the need
               for an inferior flap are determined by several factors, most notably perforation position and size relative to
               nasal size. The left superior flap is the most consequential flap in this technique owing to its robust
               vascularity and thickness, as well as the degree of advancement that can be achieved compared to the
               inferior flap. Furthermore, mucosa from the undersurface of the ULC can be incorporated into the flap to
               increase width and achieve complete, tension-free defect coverage for relatively larger (vertical height)
                                                                     [16]
               perforations and those that approach the internal valve angle  [Figure 5]. Prior rhinoplastic surgery, in
               which the upper lateral cartilages were separated from the septum, with or without spreader graft
               placement, interferes with the intact elevation of ULC mucosa utilizing an endonasal approach. An
               alternative, non-incisional technique that utilizes upper lateral cartilage mucosa has been described when
                                               [5]
               using an open approach for the repair  [Figure 6].
               Placement of an interposition graft completes the standard 3-layer repair. The often-stated primary function
               of the interposition graft is to provide scaffold support for mucosal migration in the event of a suture
               closure dehiscence or incomplete coverage of the defect’s cartilage margin following flap advancement and
               suturing. Neovascularization of the graft may improve repair healing . Our choice of autologous
                                                                               [12]
               temporalis  fascia,  septal  cartilage/bone,  or  auricular  perichondrium  is  influenced  by  clinical
               circumstances . The amount of septal cartilage or bone available for interpositional grafting may be
                           [17]
               insufficient following septoplasty. Fascia is frequently used for patients with a history of prior surgery or
               with larger perforations. Temporalis fascia is easily harvested with minimal morbidity and risk. Auricular
               cartilage that is harvested for concurrent valve or dorsal augmentation surgery can provide a perichondrium
                                                [18]
               graft and avoid a temporal donor site . A review of graft material selection in our bilateral flap repairs
                                                                                                [17]
               found no significant difference between autologous graft application and closure outcomes . Another
               attempt at closure following a failed repair can be extremely difficult, or impossible. The addition of a graft
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