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Black et al. Plast Aesthet Res 2023;10:31                                   Plastic and
               DOI: 10.20517/2347-9264.2023.04
                                                                                Aesthetic Research




               Review                                                                        Open Access



               Mitigating the impact of skin necrosis in
               reconstruction after nipple-sparing mastectomy


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               Grant G. Black , Yunchan Chen     , Marcos Lu Wang   , Karina Condez, David M. Otterburn
               Division of Plastic and Reconstructive Surgery, NewYork-Presbyterian/Weill Cornell Medical Center, New York, NY 10065, USA.
               #
                Authors contributed equally.
               Correspondence to: Dr. David M. Otterburn, Division of Plastic and Reconstructive Surgery, NewYork-Presbyterian/Weill
               Cornell Medical Center, 525 East 68th Street, New York, NY 10065, USA. E-mail: dmo9004@med.cornell.edu
               How to cite this article: Black GG, Chen Y, Wang ML, Condez K, Otterburn DM. Mitigating the impact of skin necrosis in
               reconstruction after nipple-sparing mastectomy. Plast Aesthet Res 2023;10:31. https://dx.doi.org/10.20517/2347-9264.2023.04

               Received: 17 Jan 2023  Revised: 22 May 2023  Accepted: 25 Jun 2023  Published: 28 Jun 2023
               Academic Editor: Gordon Kwanlyp Lee  Copy Editor: Yanbing Bai  Production Editor: Yanbing Bai


               Abstract
               Skin flap necrosis is a common postoperative complication after breast reconstruction, with an incidence of up to
               43.4% among patients undergoing nipple-sparing mastectomy. Necrosis can adversely impact aesthetics due to
               the need to excise nonviable tissue, and increase the risks of infection, implant loss, nipple-areola complex sacrifice
               and malposition. Patient-specific factors including age, body mass index, and breast size may affect the risk of
               necrosis. Mastectomy and reconstruction techniques (i.e., choosing between skin- and nipple-sparing mastectomy,
               and between autologous and alloplastic reconstruction) may also influence necrosis rates. Intraoperative measures
               such as indocyanine green angiography and autologous skin banking, and the postoperative use of nitroglycerin
               paste for high-risk patients and warming blankets for autologous reconstruction are methods to help prevent and
               minimize the morbidity of skin necrosis. Herein, we share our institution’s approaches to predicting and mitigating
               skin necrosis, and methods of optimizing outcomes for breast reconstruction patients.

               Keywords: Mastectomy, breast reconstruction, necrosis, autologous flap, implant




               INTRODUCTION
               Breast cancer is one of the most common forms of neoplasia in women; approximately 1 in 8 will develop it
                            [1]
               in their lifetime . The number of mastectomies performed each year is rising both as a factor of the growing






                           © The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0
                           International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing,
                           adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as
               long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and
               indicate if changes were made.

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