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Page 12 of 17           Cevallos et al. Plast Aesthet Res 2023;10:30  https://dx.doi.org/10.20517/2347-9264.2023.01

               system with infrared systems to address lower image resolution challenges posed by illumination changes
               and patient movement [136,137] . This study demonstrated earlier detection of vascular congestion compared to
               manual observation. Kim et al. utilized a novel negative pressure wound therapy technique using a
               transparent film to monitor the entire flap, allowing for the examination of flap color changes, capillary
               refilling status, and flap warmth without missing any portions of the flap . This technique has been shown
                                                                            [30]
                                                 [30]
               to reduce monitoring time and costs . Videocapillaroscopy technology shows further promise in
               evaluating circulatory changes on the skin surfaces of free flaps while deliberately clamping pedicle
                     [138]
               vessels . Bucknor et al. described a novel, non-invasive, optical oxygen-sensing liquid bandage for post-
               operative monitoring in autologous breast reconstruction . This technique uses a camera to continuously
                                                                [139]
               capture the intensity of oxygen phosphorescence and fluorescence. Hummelink et al. used a “free flap
                                                                                       [140]
               patch” adherent to a flap to continuously measure temperature and tissue saturation . The development
               of novel, patient-friendly wearable wireless monitors is ongoing, promising rapid and real-time insights into
               tissue perfusion.


               CONCLUSION
               Careful post-operative monitoring of free flaps following breast reconstructive surgery is crucial for
               determining procedural success. While the clinical examination remains the gold standard for post-
               operative flap monitoring, various adjuncts exist to complement and enhance our understanding of flap
               perfusion.


               DECLARATIONS
               Authors’ contributions
               Made substantial contributions to the conception and design of the study and performed data analysis and
               interpretation: Cevallos PC, Najafali D, Johnstone TM
               Performed data acquisition, as well as provided administrative, technical, and material support: Borrelli MR,
               Manrique OJ, Lee GK, Nazerali RS

               Availability of data and materials
               Not applicable.


               Financial support and sponsorship
               None.


               Conflicts of interest
               All authors declared that there are no conflicts of interest.


               Ethical approval and consent to participate
               Not applicable.


               Consent for publication
               Not applicable.


               Copyright
               © The Author(s) 2023


               REFERENCES
               1.       Saber AY, Hohman HM, Dreyer MA. Basic flap design. Available from: https://www.ncbi.nlm.nih.gov/books/NBK563252/ [Last
                    accessed on 19 Jun 2023].
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