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Kafle et al. Neuroimmunol Neuroinflammation 2018;5:24 I http://dx.doi.org/10.20517/2347-8659.2018.10 Page 7 of 8

index of suspicion is required in patients with features of raised ICP. Burrhole with aspiration is an excellent
option for surgical management. Major craniotomy and excision should be preserved for multiloculated,
recurrent, large size abscess cavities only. Culture positivity is very low, so longer broad spectrum intravenous
and/or oral antibiotics help in early resolution. Involvement of the otorhinolaryngology team to address the
primary source has further helped improve outcomes in cases of otogenic brain abscess.

DECLARATIONS
Authors’ contributions
Collected all data: Kafle P, Sharma MR, Shilpakar SK, Sedain G
Followed all the patients and analyzed: Kafle P, Pradhanang A, Shrestha RK, Bhandari BR
Critical analysis, language editing and final approval: Groves C

Availability of data and materials
The data presented is original and obtained in our laboratory. It is available with the authors and can be
made available if required.

Financial support and sponsorship
None.

Conflicts of interest
All authors declared that there are no conflicts of interest.

Ethical approval and consent to participate
All treatment and study were performed in compliance with our institutional standard and the Declaration
of Helsinki and consent was taken for all patients before treatment.

Consent for publication
Not applicable.

Copyright
© The Author(s) 2018.

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