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Zarei. Neuroimmunol Neuroinflammation 2018;5:13 I http://dx.doi.org/10.20517/2347-8659.2018.02 Page 7 of 10
Healthy men Healthy women Schizophrenia men Schizophrenia women
Healthy men Healthy women Schizophrenia men Schizophrenia women
Figure 4. Right precentral gyrus functional connectivity difference between healthy controls and patients with schizophrenia (controls >
schizophrenia)
to examine the aberrant functional brain connectome in schizophrenia which contains raw anatomical and
functional MR data from 72 patients with schizophrenia and 75 healthy controls, ranging in age from 18 to
65 years old. We can summarize our results as follows: The precentral gyrus has abnormal communication
with thalamus, hippocampus, pPaHC, pSMG and mPFC (P = 0.05). The right precentral gyrus has unusual
connectivities with Hippocampus l, pPaHC l Thalamus l, Thalamus r and pSMG r. The right precentral gyrus
has unbalanced connectivities with Hippocampus l, pPaHC l, Thalamus r, MPFC, pSMG r, Hippocampus r and
Thalamus l. The connectivity impairments of the PreCG in schizophrenia are different for male and female
patients. This information is expected to provide a better understanding of altered functional connectivity
of primary motor cortex in schizophrenia.
