Page 64 - Read Online
P. 64
3. Dick JE. Stem cell concepts renew cancer research. Blood Fuhlbrigge RC, Kupper TS, Sayegh MH, Frank MH. Identification
2008;112:4793-807. of cells initiating human melanomas. Nature 2008;451:345-9.
4. Hunter SG, Zhuang G, Brantley-Sieders D, Swat W, Cowan CW, 24. Gunther HS, Schmidt NO, Phillips HS, Kemming D, Kharbanda S,
Chen J. Essential role of Vav family guanine nucleotide exchange Soriano R, Modrusan Z, Meissner H, Westphal M, Lamszus K.
factors in EphA receptor-mediated angiogenesis. Mol Cell Biol Glioblastoma-derived stem cell-enriched cultures form distinct
2006;26:4830-42. subgroups according to molecular and phenotypic criteria.
5. Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T, Oncogene 2008;27:2897-909.
Caceres-Cortes J, Minden M, Paterson B, Caligiuri MA, Dick JE. 25. Qiu B, Zhang D, Tao J, Wu A, Wang Y. A simplified and modified
A cell initiating human acute myeloid leukaemia after transplantation procedure to culture brain glioma stem cells from clinical specimens.
into SCID mice. Nature 1994;367:645-8. Oncol Lett 2012;3:50-4.
6. Bonnet D, Dick JE. Human acute myeloid leukemia is organized 26. Yu SC, Ping YF, Yi L, Zhou ZH, Chen JH, Yao XH, Gao L, Wang JM,
as a hierarchy that originates from a primitive hematopoietic cell. Bian XW. Isolation and characterization of cancer stem cells from a
Nat Med 1997;3:730-7. human glioblastoma cell line U87. Cancer Lett 2008;265:124-34.
7. Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, 27. Read TA, Fogarty MP, Markant SL, McLendon RE, Wei Z, Ellison DW,
Dewhirst MW, Bigner DD, Rich JN. Glioma stem cells promote Febbo PG, Wechsler-Reya RJ. Identification of CD15 as a marker
radioresistance by preferential activation of the DNA damage for tumor-propagating cells in a mouse model of medulloblastoma.
response. Nature 2006;444:756-60. Cancer Cell 2009;15:135-47.
8. Hambardzumyan D, Squatrito M, Holland EC. Radiation resistance 28. Tchoghandjian A, Baeza N, Colin C, Cayre M, Metellus P, Beclin C,
and stem-like cells in brain tumors. Cancer Cell 2006;10:454-6. Ouafik L, Figarella-Branger D. A2B5 cells from human glioblastoma
9. Gómez-Gaviro MV, Lovell-Badge R, Fernández-Avilés F, have cancer stem cell properties. Brain Pathol 2010;20:211-21.
Lara-Pezzi E. The vascular stem cell niche. J Cardiovasc Transl Res 29. Ogden AT, Waziri AE, Lochhead RA. Identification of
2012;5:618-30. A2B5+CD133 tumor initiating cells in adult human gliomas.
−
10. Yoshida S, Sukeno M, Nabeshima Y. A vasculature-associated niche Neurosurgery 2008;62:505-15.
for undifferentiated spermatogonia in the mouse testis. Science 30. Bao S, Wu Q, Li Z, Sathornsumetee S, Wang H, McLendon RE,
2007;317:1722-6. Hjelmeland AB, Rich JN. Targeting cancer stem cells through
11. Gilbertson RJ, Rich JN. Making a tumour’s bed: glioblastoma stem L1CAM suppresses glioma growth. Cancer Res 2008;68:6043-8.
cells and the vascular niche. Nat Rev Cancer 2007;7:733-6. 31. Ogden AT, Waziri AE, Lochhead RA, Fusco D, Lopez K, Ellis JA,
12. Li Z, Bao S, Wu Q, Wang H, Eyler C, Sathornsumetee S, Shi Q, Kang J, Assanah M, McKhann GM, Sisti MB, McCormick PC,
Cao Y, Lathia J, McLendon RE, Hjelmeland AB, Rich JN. Canoll P, Bruce JN. Identification of A2B5+CD133- tumor-initiating
Hypoxia-inducible factors regulate tumorigenic capacity of glioma cells in adult human gliomas. Neurosurgery 2008;62:505-14.
stem cells. Cancer Cell 2009;15:501-13. 32. Clément V, Marino D, Cudalbu C, Hamou MF, Mlynarik V, de Tribolet N,
13. Wang J, Sakariassen PO, Tsinkalovsky O, Immervoll H, Boe SO, Dietrich PY, Gruetter R, Hegi ME, Radovanovic I. Marker-independent
Svendsen A, Prestegarden L, Rosland G, Thorsen F, Stuhr L, identification of glioma-initiating cells. Nat Methods 2010;7:224-8.
Molven A, Bjerkvig R, Enger PO. CD133 negative glioma cells 33. Dlugosz AA, Talpaz M. Following the Hedgehog to new cancer
form tumors in nude rats and give rise to CD133 positive cells. Int therapies. N Engl J Med 2009;361:1202-5.
J Cancer 2008;122:761-8. 34. Yoo YA, Kang MH, Lee HJ, Kim BH, Park JK, Kim HK, Kim JS,
14. Reardon DA, Wen PY, Desjardins A, Batchelor TT, Vredenburgh JJ. Oh SC. Sonic Hedgehog pathway promotes metastasis and
Glioblastoma multiforme: an emerging paradigm of anti-VEGF lymphangiogenesis via activation of Akt, EMT, and MMP-9 pathway
therapy. Expert Opin Biol Ther 2008;8:541-53. in gastric cancer. Cancer Res 2011;71:7061-70.
15. Jamal M, Rath BH, Tsang PS, Camphausen K, Tofilon PJ. The brain 35. Uchida H, Arita K, Yunoue S, Yonezawa H, Shinsato Y, Kawano H,
microenvironment preferentially enhances the radioresistance of Hirano H, Hanaya R, Tokimura H. Role of sonic Hedgehog signaling
CD133(+) glioblastoma stem-like cells. Neoplasia 2012;14:150-8. in migration of cell lines established from CD133-positive malignant
16. Hardee ME, Marciscano AE, Medina-Ramirez CM, Zagzag D, glioma cells. J Neurooncol 2011;104:697-704.
Narayana A, Lonning SM, Barcellos-Hoff MH. Resistance of 36. Po A, Ferretti E, Miele E, De Smaele E, Paganelli A, Canettieri G,
glioblastoma-initiating cells to radiation mediated by the tumor Coni S, Di Marcotullio L, Biffoni M, Massimi L, Di Rocco C,
microenvironment can be abolished by inhibiting transforming Screpanti I, Gulino A. Hedgehog controls neural stem cells through
growth factor-β. Cancer Res 2012;72:4119-29. p53-independent regulation of Nanog. EMBO J 2010;29:2646-58.
17. Liu G, Yuan X, Zeng Z, Tunici P, Ng H, Abdulkadir IR, Lu L, Irvin D, 37. Hsieh A, Ellsworth R, Hsieh D. Hedgehog/GLI1 regulates IGF
Black KL, Yu JS. Analysis of gene expression and chemoresistance of dependent malignant behaviors in glioma stem cells. J Cell Physiol
CD133+cancer stem cells in glioblastoma. Mol Cancer 2006;5:67. 2011;226:1118-27.
18. Piccirillo SG, Reynolds BA, Zanetti N, Lamorte G, Binda E, 38. Ulasov IV, Nandi S, Dey M, Sonabend AM, Lesniak MS. Inhibition
Broggi G, Brem H, Olivi A, Dimeco F, Vescovi AL. Bone of Sonic Hedgehog and Notch pathways enhances sensitivity of
morphogenetic proteins inhibit the tumorigenic potential of human CD133(+) glioma stem cells to temozolomide therapy. Mol Med
brain tumour-initiating cells. Nature 2006;444:761-5. 2011;17:103-12.
19. Kim RK, Yoon CH, Hyun KH, Lee H, An S, Park MJ, Kim MJ, 39. Takezaki T, Hide T, Takanaga H, Nakamura H, Kuratsu J, Kondo T.
Lee SJ. Role of lymphocyte-specific protein tyrosine kinase (LCK) Essential role of the Hedgehog signaling pathway in human
in the expansion of glioma-initiating cells by fractionated radiation. glioma-initiating cells. Cancer Sci 2011;102:1306-12.
Biochem Biophys Res Commun 2010;402:631-6. 40. Kosik KS. The neuronal microRNA system. Nat Rev Neurosci
20. Jamal M, Rath BH, Williams ES, Camphausen K, Tofilon PJ. 2006;7:911-20.
Microenvironmental regulation of glioblastoma radioresponse. Clin 41. Fareh M, Turchi L, Virolle V, Debruyne D, Almairac F, De-La-Forest
Cancer Res 2010;16:6049-59. Divonne S, Paquis P, Preynat-Seauve O, Krause KH, Chneiweiss H,
21. Dean M, Fojo T, Bates S. Tumour stem cells and drug resistance. Virolle T. The miR 302-367 cluster drastically affects self-renewal
Nat Rev Cancer 2005;5:275-84. and infiltration properties of glioma-initiating cells through CXCR4
22. Clement V, Sanchez P, de Tribolet N, Radovanovic I, Ruiz i repression and consequent disruption of the SHH-GLI-NANOG
Altaba A. HEDGEHOG-GLI1 signaling regulates human glioma network. Cell Death Differ 2012;19:232-44.
growth, cancer stem cell self-renewal, and tumorigenicity. Curr Biol 42. Sengupta R, Dubuc A, Ward S, Yang L, Northcott P, Woerner BM,
2007;17:165-72. Kroll K, Luo J, Taylor MD, Wechsler-Reya RJ, Rubin JB. CXCR4
23. Schatton T, Murphy GF, Frank NY, Yamaura K, Waaga-Gasser AM, activation defines a new subgroup of sonic Hedgehog-driven
Gasser M, Zhan Q, Jordan S, Duncan LM, Weishaupt C, medulloblastoma. Cancer Res 2012;72:122-32.
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