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Page 12 of 19            Masiero et al. Mini-invasive Surg 2022;6:4  https://dx.doi.org/10.20517/2574-1225.2021.104































































                Figure 4. Annulus covering range and vessels diameter requirements of different balloon expandable (A) and self-expandable (B)
                                                                                      2+
                THVs. *MVD: Minimum vessel diameter requirements (MSCT derived), excluding circumferential Ca ; THVs: transcatheter heart
                valves; MSCT: multi-slice computed tomography.

               distal tip of the wire forming a 2 mm J bend; it can easily maneuver in smaller ventricles, while the
               Safari2TM wire is available in three different loop sizes, offering the possibility to select the curve size
               according to the size of the ventricle.


               Pharmacological management
               The choice of the optimal antithrombotic regimen peri- and post-TAVI is of utmost importance [Figure 6].
               Thromboembolic and bleeding complications are frequent and can be potentially life-threatening [51,75,76] .
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