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[24]
pacemaker rate with self-expandable valves . Discharge policy was defined by protocol but, in reality, per
treating physician’s discretion, and referring hospitals did not collect reasons for prolonged stay; variation
in discharge policy among different physicians (e.g., due to difference in experience) might have influenced
these results. However, to the best of our knowledge, this is the first study comparing three different
discharge pathways. Our findings require confirmation in a prospective multicenter design.

Conclusions
Early discharge pathways home and to referral hospitals are safe and help streamline TAVI programs. LOS
in referring hospitals may be further reduced.

DECLARATIONS
Authors’ contributions
Study model design and study protocol writing: de Ronde-Tillmans MJ
Experiment implementation: van Wiechen MP, de Ronde-Tillmans MJ
Statistical analysis and first draft writing: van Wiechen MP
Original idea conceiving and project supervision: Van Mieghem NM
Critical feedback and research analysis: van Wiechen MP, de Ronde-Tillmans MJ, Van Mieghem NM

Availability of data and materials
The data that support the findings of this study are available from the corresponding author upon
reasonable request.

Financial support and sponsorship
None.

Conflict of interest
Nicolas M. Van Mieghem received research grants from Abbott, Boston Scientific, Edwards, Essential
Medical/Teleflex, Medtronic, PulseCath BV. All other authors declared there are no conflict of interest.

Ethical approval and consent to participate
The study was conducted in accordance with the declaration of Helsinki and did not fall under the scope of
the Medical Research Involving Human Subjects Act. All patients consented to the procedure and
subsequent data analysis for research purposes.

Consent for publication
All patients consented to the procedure and subsequent data analysis for research purposes.

Copyright
© The Author(s) 2022.

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