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Khokhar et al. Mini-invasive Surg 2022;6:2 Mini-invasive Surgery
DOI: 10.20517/2574-1225.2021.97

Review Open Access

Prevention and management of peri-procedural

TAVR complications

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1,2
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Arif A. Khokhar , Rossella Ruggiero , Kailash Chandra , Alessandro D’Agostino , Marco Toselli , Antonio
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Mangieri , Dariusz Dudek , Antonio Colombo , Francesco Giannini 3
1
Department of Cardiology, Imperial College Healthcare NHS Trust, London W21NY, UK.
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Digital Innovations & Robotics Hub, Krakow 31-514, Poland.
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Interventional Cardiology Unit, GVM Care & Research Maria Cecilia Hospital, Cotignola 48033, Italy.
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Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan 20090, Italy.
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Cardio Center, Humanitas Research Hospital, IRCCS, Rozzano, Milan 20090, Italy.
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Institute of Cardiology, Jagiellonian University Medical College, Krakow 31-008, Poland.
Correspondence to: Dr. Arif A. Khokhar, Department of Cardiology, Imperial College Healthcare NHS Trust, Praed Street,
London W21NY, UK. E-mail: arifkhokhar@doctors.org.uk
How to cite this article: Khokhar AA, Ruggiero R, Chandra K, D’Agostino A, Toselli M, Mangieri A, Dudek D, Colombo A,
Giannini F. Prevention and management of peri-procedural TAVR complications. Mini-invasive Surg 2022;6:2.
https://dx.doi.org/10.20517/2574-1225.2021.97
Received: 19 Aug 2021 First Decision: 4 Nov 2021 Revised: 11 Nov 2021 Accepted: 6 Dec 2021 Published: 6 Jan 2022
Academic Editor: Andrea Scotti Copy Editor: Xi-Jun Chen Production Editor: Xi-Jun Chen
Abstract
Transcatheter aortic valve replacement (TAVR) is a safe and effective treatment strategy for severe aortic
stenosis. However, peri-procedural complications can have a significant impact on acute and longer-term
morbidity and mortality. Therefore, this review article provides a practical overview on how to prevent and manage
the common and also rare but life-threatening peri-procedural TAVR complications.

Keywords: TAVR, complications, peri-procedural planning

INTRODUCTION
Transcatheter aortic valve replacement (TAVR) is a recommended treatment strategy for patients with
severe aortic stenosis (AS) across all surgical risk profiles. As TAVR expands towards lower-risk younger
patients, the number of procedures is set to dramatically increase. Knowledge of how to prevent and
manage peri-procedural complications, which can be life-threatening or have a significant impact upon

© The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0
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