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Table 1. Selected studies evaluating oncologic outcomes after robot-assisted radical cystectomy

Study
Ref. Year Comparison Setting Primary outcome Pertinent secondary outcome(s)
design
Comparative studies, randomized
[6,7]
RAZOR trial, multiple authors 2020, ORC vs. RARC RCT Multi center 2-year PFS TTR, PFS, OS
2018
[8]
CORAL trial, Khan et al. 2020 ORC vs. RARC vs. RCT Single center 5-year RFS, CSS, OS Surgical margin, recurrence patterns
LRC
[9]
Bochner et al. 2018 ORC vs. RARC RCT Single center 90-day complication RFS, CSS, OS, recurrence patterns
[10]
Parekh et al. 2012 ORC vs. RARC RCT Single center Surgical margin Quality of life
Total lymph node yield Functional recovery
[11]
Nix et al. 2010 ORC vs. RARC RCT Single center Lymph node yield Demographics, perioperative, pathologic results, narcotic
use
Comparative studies, non-randomized
[12]
RACE study, Wijburg et al. 2021 ORC vs. RARC Prospective Multi center 90-day complication HRQOL, complications, clinical outcomes including
surgical margin
[13]
Asil et al. 2021 ORC vs. RARC Retrospective Multi center Intraoperative and postoperative endpoints Surgical margin, lymph node yield
[14]
Ip et al. 2020 ORC vs. RARC Retrospective Single center RFS, OS Perioperative and pathologic outcomes
[15]
Zhang et al. 2020 ORC vs. RARC Retrospective Single center Perioperative outcomes, complications Pathologic outcomes, overall survival
[16]
Faraj et al. 2019 ORC vs. RARC Retrospective Single center RFS, OS Recurrence patterns, predictors of primary outcome
[17]
Moschini et al. 2019 ORC vs. RARC Retrospective Multicenter Surgical margin status Predictors of surgical margin status
[18]
Simone et al. 2018 ORC vs. RARC, Retrospective Single center RFS, CSS, OS Complications, perioperative and pathologic outcomes
ICUD only
[19]
Hanna et al. 2018 ORC vs. RARC Retrospective Population Intraoperative and postoperative endpoints Descriptors and predictors of robotic surgical approach
registry
[20]
Gandagli et al. 2016 ORC vs. RARC Retrospective Multi center RFS, CSS, OS Complications, perioperative and pathologic outcomes,
recurrence
[21]
Tan et al. 2016 ORC vs. RARC Retrospective Single center RFS Recurrence patterns, CSS, OS
[22]
Matulewicz et al. 2016 ORC vs. RARC Retrospective Population Surgical margin status, lymph node yield Primary outcome variables as predictors of survival
registry
[23]
Nguyen et al. 2015 ORC vs. RARC Retrospective Single center RFS Recurrence patterns at 2 years
[24]
Atmaca et al. 2015 ORC vs. RARC, Retrospective Single center Demographics, functional, intraoperative Surgical margin, lymph node yield
ICUD only outcomes
Non-comparative studies
[25]
IRCC, Elsayed et al. 2021 RARC only Retrospective Multicenter RFS, LRFS, DMFS, OS Recurrence patterns, predictors of recurrent free survival
[26]
Brassetti et al. 2020 RARC, ICUD only Retrospective Multicenter RFS, CSS, OS Surgical margin, lymph node yield, predictors of survival
[27]
IRCC, Hussein et al. 2019 RARC only Retrospective Multicenter 10-year RFS, CSS, OS Surgical margin, lymph node yield, predictors of survival