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Chen et al. Mini-invasive Surg 2018;2:43  I  http://dx.doi.org/10.20517/2574-1225.2018.42                                          Page 5 of 12


                            Table 1. Baseline characteristics and perioperative outcomes of 60 patients with low-lying
                            rectal cancer who underwent robotic-assisted total mesorectal excision
                            Characteristics                                    Value/number
                            Age (years, median) (range)                         62 (32-87)
                            Gender
                               Female                                           24 (40%)
                               Male                                             36 (60%)
                            Distance from anal verge (cm, median) (range)       3.5 (1-5)
                            Pre-operation CCRT
                               Yes                                              49 (81.7%)
                               No                                               11 (18.3%)
                            Pre-operation chemotherapy regimen                  49
                               FOLFOX                                           36 (73.5%)
                               Fluoropyrimidine-based                           13 (26.5%)
                            Time interval between radiotherapy completion and robotic surgery (day,   91 (47-363)
                            median) (range) (49 patients undergoing pre-operation chemotherapy)

                            ASAclassification
                               II                                               36 (60%)
                               III                                              24 (40%)
                            BMI kg/m  (median) (range)                          23.07 (17.50-30.9)
                                   2
                            Procedure
                               LAR                                              19 (31.7%)
                               ISR                                              37 (61.7%)
                               APR                                              4 (6.6%)
                            Protective diverting colostomy
                               Yes                                              45 (75%)
                               No                                               15 (25%)
                            Docking time (min, median) (range)                  5 (3-10)
                            Console time (min, median) (range)                  215 (150-527)
                            Operation time (min, median) (range)                320 (240-710)
                            Estimated blood loss (mL, median)                   95 (15-450)
                            Time of first flatus passage (day) (median, range)  2 (1-10)
                            Time of resuming soft diet (day) (median, range)    4 (2-13)
                            Postoperative hospital stay (day) (median, range)   6 (5-30)
                            Postoperative first day VAS pain score (median, range)  3 (1-7)

               CCRT: concurrent chemoradiotherapy; ASA: American Society of Anesthesiologists; BMI: body mass index; LAR: low anterior resection;
               ISR: intersphincteric resection; APR: abdominoperineal resection; VAS: visual analog scale

               verting loop transverse colostomy was performed in 45 patients, including 37 patients and 8 patients who
               underwent ISR and LAR, respectively. The median operating time was 320 min (range, 240-710), with a
               median blood loss of 95 mL (range, 15-450). Median length of stay was 6 days (range 5-30). No mortality
               was observed within 30 days following the procedure. Furthermore, no intraoperative complications or
               conversion to open surgery were noted.

               Postoperative complications
               Table 2 presents postoperative complications. Three patients required reoperation within 30 days following
               the procedure, two for anastomotic leak, and one for postoperative bleeding. Transverse loop colostomy
               was performed for anastomotic leak, and we monitored postoperative bleeding through laparotomy. Other
               complications included prolonged ileus (n = 3), urethral injury (n = 1), and coloanal anastomosis stenosis (n
               = 2). We used colonfiberoscope dilation for the two patients with coloanal anastomosis stenosis. The others
               morbidities recovered uneventfully after conservative treatment.


               Pathological and oncological outcomes
               The pathological characteristics and oncological outcomes of all 60 patients are listed in Table 3. Preopera-
               tive clinical staging demonstrated that the majority of the patients had locally advanced rectal cancer: T3,
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