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Page 301 Berber et al. J Transl Genet Genom 2021;5:292-303 https://dx.doi.org/10.20517/jtgg.2021.35

School of Medicine) for providing us with a detailed differentiation protocol. We would also like to thank
Nico Hertl for his valuable help and advice in hiPSC maintenance.

Authors’ contributions
Designed the study, performed data acquisition, analysis and interpretation, prepared the manuscript:
Berber P
Made substantial contributions to the discussion of content, provided feedback and performed manuscript
editing: Milenkovic A
Made substantial contributions to method optimization, provided excellent technical support: Michaelis L
Conceptualized and supervised the study, helped with data interpretation and condensed presentation in
Tables and Figures, performed manuscript editing and finalization: Weber BHF
Made final approval of the manuscript: Milenkovic A, Michaelis L, Weber BHF

Availability of data and materials
Not applicable.

Financial support and sponsorship
The study was supported in parts by a grant from the German Research Foundation (DFG) to BHFW
(WE1259/32-1) and institutional funds of the Institute of Human Genetics (Title 77). The funding body had
no role in the experimental design, collection, analysis and interpretation of data, and writing of the
manuscript. The FV3000 confocal microscope was funded by a grant (INST 89/506-1 FUGG, 91b GG) from
the Deutsche Forschungsgemeinschaft (DFG).

Conflicts of interest
All authors declared that there are no conflicts of interest.

Ethical approval and consent to participate
The reprogramming and differentiation of hiPSC from human donor material were approved by the local
ethics review board of the University of Regensburg, Germany (reference No. 11-101-0228) and have been
performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its
later amendments. Informed consent was given by the proband participating in the study.

Consent for publication
Not applicable.

Copyright
© The Author(s) 2021.

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