Page 28 - Read Online

Puyana et al. J Transl Genet Genom 2022;6:223-239 https://dx.doi.org/10.20517/jtgg.2021.51 Page 235

Authors’ contributions
Conceived and designed study: Puyana C, Hu JJ
Data analysis and interpretation: Puyana C, Schindler E, Lee E, Hu JJ
Drafted and revised the manuscript: Puyana C, Schindler E, Lee E, Hu JJ
All authors read and approved the manuscript.

Availability of data and materials
The data that support the findings of this manuscript are available from the corresponding author upon
request.

Financial support and sponsorship
This study was supported by a grant funded by the National Institutes of Health (R01CA135288 to Hu JJ).

Conflicts of interest
All authors declared that there are no conflicts of interest.

Ethical approval and consent to participate
Study protocols were approved by the Institutional Review Board at the University of Miami. Informed
consent was obtained from all study participants at the time of enrollment.

Consent for publication
Not applicable.

Copyright
© The Author(s) 2022.

REFERENCES
1. Kim A, Scharf K, Senthil M, Solomon N, Garberoglio C, Lum SS. The prevalence of overweight and obesity in a breast clinic
population: consideration for weight loss as a therapeutic intervention. Surg Obes Relat Dis 2014;10:348-53. DOI PubMed
2. Barone I, Giordano C, Bonofiglio D, Andò S, Catalano S. The weight of obesity in breast cancer progression and metastasis: clinical
and molecular perspectives. Semin Cancer Biol 2020;60:274-84. DOI PubMed
3. Lee K, Kruper L, Dieli-Conwright CM, Mortimer JE. The impact of obesity on breast cancer diagnosis and treatment. Curr Oncol
Rep 2019;21:41. DOI PubMed PMC
4. White KK, Park SY, Kolonel LN, Henderson BE, Wilkens LR. Body size and breast cancer risk: the Multiethnic Cohort. Int J Cancer
2012;131:E705-16. DOI PubMed PMC
5. Lopez R, Agullo P, Lakshmanaswamy R. Links between obesity, diabetes and ethnic disparities in breast cancer among Hispanic
populations. Obes Rev 2013;14:679-91. DOI PubMed
6. Society AC. Cancer facts and figures. Atlanta: American Cancer Society, 2013.
7. Ligibel J. Obesity and breast cancer. Oncology (Williston Park) 2011;25:994-1000. PubMed
8. Picon-Ruiz M, Morata-Tarifa C, Valle-Goffin JJ, Friedman ER, Slingerland JM. Obesity and adverse breast cancer risk and outcome:
mechanistic insights and strategies for intervention. CA Cancer J Clin 2017;67:378-97. DOI PubMed PMC
9. Benedetto C, Salvagno F, Canuto EM, Gennarelli G. Obesity and female malignancies. Best Pract Res Clin Obstet Gynaecol
2015;29:528-40. DOI PubMed
10. Shu X, Wu L, Khankari NK, et al; Breast Cancer Association Consortium. Associations of obesity and circulating insulin and glucose
with breast cancer risk: a Mendelian randomization analysis. Int J Epidemiol 2019;48:795-806. DOI PubMed PMC
11. Rodriguez-Gil JL, Takita C, Wright J, et al. Inflammatory biomarker C-reactive protein and radiotherapy-induced early adverse skin
reactions in patients with breast cancer. Cancer Epidemiol Biomarkers Prev 2014;23:1873-83. DOI PubMed PMC
12. Chan DSM, Vieira AR, Aune D, et al. Body mass index and survival in women with breast cancer-systematic literature review and
meta-analysis of 82 follow-up studies. Ann Oncol 2014;25:1901-14. DOI PubMed PMC
13. Islami F, Goding Sauer A, Miller KD, et al. Proportion and number of cancer cases and deaths attributable to potentially modifiable
risk factors in the United States. CA Cancer J Clin 2018;68:31-54. DOI PubMed
14. DeSantis C, Ma J, Bryan L, Jemal A. Breast cancer statistics, 2013. CA Cancer J Clin 2014;64:52-62. DOI PubMed
15. Curtis E, Quale C, Haggstrom D, Smith-Bindman R. Racial and ethnic differences in breast cancer survival: how much is explained