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Moore et al. J Transl Genet Genom 2021;5:200-217 Journal of Translational
DOI: 10.20517/jtgg.2021.08
Genetics and Genomics

Original Article Open Access

Genome-wide homozygosity and risk of four non-
Hodgkin lymphoma subtypes

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Amy Moore , Mitchell J. Machiela , Moara Machado , Sophia S. Wang , Eleanor Kane , Susan L. Slager ,
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Weiyin Zhou , Mary Carrington , Qing Lan , Roger L. Milne 9,10,11 , Brenda M. Birmann , Hans-Olov
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Adami 13,14,15 , Demetrius Albanes , Alan A. Arslan 16,17,18 , Nikolaus Becker , Yolanda Benavente 20,21 , Simonetta
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Bisanzi , Paolo Boffetta 23,24 , Paige M. Bracci , Paul Brennan , Angela R. Brooks-Wilson 27,28 , Federico
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Canzian , Neil Caporaso , Jacqueline Clavel , Pierluigi Cocco , Lucia Conde , David G. Cox , Wendy
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Cozen 34,35 , Karen Curtin , Immaculata De Vivo 12,14 , Silvia de Sanjose 1,21 , Lenka Foretova , Susan M.
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Gapstur , Hervé Ghesquières 39,40 , Graham G. Giles 9,10,11 , Martha Glenn , Bengt Glimelius , Chi Gao ,
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Thomas M. Habermann , Henrik Hjalgrim , Rebecca D. Jackson , Mark Liebow , Brian K. Link , Marc
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Maynadie , James McKay , Mads Melbye 43,47 , Lucia Miligi , Thierry J. Molina , Alain Monnereau 30,50 ,
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Alexandra Nieters , Kari E. North 52,53 , Kenneth Offit , Alpa V. Patel , Sara Piro , Vignesh Ravichandran ,
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Elio Riboli , Gilles Salles 40,56,57 , Richard K. Severson , Christine F. Skibola , Karin E. Smedby 60,61 , Melissa
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C. Southey , John J. Spinelli 63,64 , Anthony Staines , Carolyn Stewart , Lauren R. Teras , Lesley F.
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Tinker , Ruth C. Travis , Claire M. Vajdic , Roel C. H. Vermeulen 69,70 , Joseph Vijai , Elisabete
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Weiderpass , Stephanie Weinstein , Nicole Wong Doo , Yawei Zhang , Tongzhang Zheng , Stephen J.
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Chanock , Nathaniel Rothman , James R. Cerhan , Michael Dean , Nicola J. Camp , Meredith Yeager ,
Sonja I. Berndt 1
1
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA.
2
Departamento de Biologia Geral, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte 31270-
901, Brazil.
3
Division of Health Analytics, City of Hope Beckman Research Institute, Duarte, CA 91010, USA.
4
Department of Health Sciences, University of York, York YO10 5DD, UK.
5
Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.
6
Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Gaithersburg,
MD 20877, USA.
7
Basic Science Program, Frederick National Laboratory for Cancer Research in the Laboratory of Integrative Cancer Immunology,
National Cancer Institute, Bethesda, MD 20892, USA.
8
Ragon Institute of MGH, Cambridge, MA 02139, USA.
9
Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria 3004, Australia.
10
Centre for Epidemiology and Biostatistics, School of Population and Global Health, The University of Melbourne, Melbourne,
Victoria 3010, Australia.
11
Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria 3800, Australia.
12
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical
School, Boston, MA 02115, USA.
13
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17176, Sweden.
14
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
15
Institute of Health and Society, Clinical Effectiveness Research Group, University of Oslo, Oslo 0315, Norway.
16
Department of Obstetrics and Gynecology, New York University School of Medicine, New York, NY 10016, USA.
17
Department of Population Health, New York University School of Medicine, New York, NY 10016, USA.
18
Perlmutter Comprehensive Cancer Center, NYU Langone Health, New York, NY 10016, USA.
19
Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Baden-Württemberg 69120, Germany.
© The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0
International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing,
adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as
long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and
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