Page 20 - Read Online

Cantone Reversal of X chromosome inactivation

Hawkins RD, Cirulli V, Ruohola-Baker H. Derivation of naive human Sterr M, Fiedler S, Demmerle J, Popken J, Leonhardt H, Brockdorff
embryonic stem cells. Proc Natl Acad Sci U S A 2014;111:4484-9. N, Cremer T, Schermelleh L, Cremer M. Three-dimensional super-
116. Theunissen TW, Powell BE, Wang H, Mitalipova M, Faddah resolution microscopy of the inactive X chromosome territory reveals a
DA, Reddy J, Fan ZP, Maetzel D, Ganz K, Shi L, Lungjangwa T, collapse of its active nuclear compartment harboring distinct Xist RNA
Imsoonthornruksa S, Stelzer Y, Rangarajan S, D’Alessio A, Zhang J, foci. Epigenetics Chromatin 2014;7:8.
Gao Q, Dawlaty MM, Young RA, Gray NS, Jaenisch R. Systematic 129. Cantone I, Dharmalingam G, Chan YW, Kohler AC, Lenhard B,
identification of culture conditions for induction and maintenance of Merkenschlager M, Fisher AG. Allele-specific analysis of cell fusion-
naive human pluripotency. Cell Stem Cell 2014;15:471-87. mediated pluripotent reprograming reveals distinct and predictive
117. Tchieu J, Kuoy E, Chin MH, Trinh H, Patterson M, Sherman SP, susceptibilities of human X-linked genes to reactivation. Genome Biol
Aimiuwu O, Lindgren A, Hakimian S, Zack JA, Clark AT, Pyle 2017;18:2.
AD, Lowry WE, Plath K. Female human iPSCs retain an inactive X 130. DeBoever C, Li H, Jakubosky D, Benaglio P, Reyna J, Olson KM,
chromosome. Cell Stem Cell 2010;7:329-42. Huang H, Biggs W, Sandoval E, D’Antonio M, Jepsen K, Matsui
118. Marchetto MC, Carromeu C, Acab A, Yu D, Yeo GW, Mu Y, Chen G, H, Arias A, Ren B, Nariai N, Smith EN, D’Antonio-Chronowska A,
Gage FH, Muotri AR. A model for neural development and treatment Farley EK, Frazer KA. Large-scale profiling reveals the influence of
of Rett syndrome using human induced pluripotent stem cells. Cell genetic variation on gene expression in human induced pluripotent
2010;143:527-39. stem cells. Cell Stem Cell 2017;20:533-46.e7.
119. Pomp O, Dreesen O, Leong DF, Meller-Pomp O, Tan TT, Zhou F, 131. Giorgetti L, Lajoie BR, Carter AC, Attia M, Zhan Y, Xu J, Chen CJ,
Colman A. Unexpected X chromosome skewing during culture and Kaplan N, Chang HY, Heard E, Dekker J. Structural organization of
reprogramming of human somatic cells can be alleviated by exogenous the inactive X chromosome in the mouse. Nature 2016; doi: 10.1038/
telomerase. Cell Stem Cell 2011;9:156-65. nature18589.
120. Tomoda K, Takahashi K, Leung K, Okada A, Narita M, Yamada NA, 132. Berletch JB, Yang F, Xu J, Carrel L, Disteche CM. Genes that escape
Eilertson KE, Tsang P, Baba S, White MP, Sami S, Srivastava D, from X inactivation. Hum Genet 2011;130:237-45.
Conklin BR, Panning B, Yamanaka S. Derivation conditions impact 133. Calabrese JM, Sun W, Song L, Mugford JW, Williams L, Yee D,
X-inactivation status in female human induced pluripotent stem cells. Starmer J, Mieczkowski P, Crawford GE, Magnuson T. Site-specific
Cell Stem Cell 2012;11:91-9. silencing of regulatory elements as a mechanism of X inactivation.
121. Kim KY, Hysolli E, Tanaka Y, Wang B, Jung YW, Pan X, Weissman Cell 2012;151:951-63.
SM, Park IH. X chromosome of female cells shows dynamic changes 134. Berletch JB, Ma W, Yang F, Shendure J, Noble WS, Disteche CM,
in status during human somatic cell reprogramming. Stem Cell Reports Deng X. Escape from X inactivation varies in mouse tissues. PLoS
2014;2:896-909. Genet 2015;11:e1005079.
122. Takashima Y, Guo G, Loos R, Nichols J, Ficz G, Krueger F, Oxley 135. Chaligne R, Popova T, Mendoza-Parra MA, Saleem MA, Gentien
D, Santos F, Clarke J, Mansfield W, Reik W, Bertone P, Smith A. D, Ban K, Piolot T, Leroy O, Mariani O, Gronemeyer H, Vincent-
Resetting transcription factor control circuitry toward ground-state Salomon A, Stern MH, Heard E. The inactive X chromosome is
pluripotency in human. Cell 2014;158:1254-69. epigenetically unstable and transcriptionally labile in breast cancer.
123. Huang K, Maruyama T, Fan G. The naive state of human pluripotent Genome Res 2015;25:488-503.
stem cells: a synthesis of stem cell and preimplantation embryo 136. Kang J, Lee HJ, Kim J, Lee JJ, Maeng LS. Dysregulation of X
transcriptome analyses. Cell Stem Cell 2014;15:410-5. chromosome inactivation in high grade ovarian serous adenocarcinoma.
124. Brady JJ, Li M, Suthram S, Jiang H, Wong WH, Blau HM. Early role PLoS One 2015;10:e0118927.
for IL-6 signalling during generation of induced pluripotent stem cells 137. Pageau GJ, Hall LL, Ganesan S, Livingston DM, Lawrence JB. The
revealed by heterokaryon RNA-Seq. Nat Cell Biol 2013;15:1244-52. disappearing Barr body in breast and ovarian cancers. Nat Rev Cancer
125. Harris H, Watkins JF, Ford CE, Schoefl GI. Artificial heterokaryons of 2007;7:628-33.
animal cells from different species. J Cell Sci 1966;1:1-30. 138. Bennett-Baker PE, Wilkowski J, Burke DT. Age-associated
126. Cantone I, Bagci H, Dormann D, Dharmalingam G, Nesterova activation of epigenetically repressed genes in the mouse. Genetics
T, Brockdorff N, Rougeulle C, Vallot C, Heard E, Chaligne R, 2003;165:2055-62.
Merkenschlager M, Fisher AG. Ordered chromatin changes and 139. Ostan R, Monti D, Gueresi P, Bussolotto M, Franceschi C, Baggio G.
human X chromosome reactivation by cell fusion-mediated pluripotent Gender, aging and longevity in humans: an update of an intriguing/
reprogramming. Nat Commun 2016;7:12354. neglected scenario paving the way to a gender-specific medicine. Clin
127. Engreitz JM, Pandya-Jones A, McDonel P, Shishkin A, Sirokman K, Sci (Lond) 2016;130:1711-25.
Surka C, Kadri S, Xing J, Goren A, Lander ES, Plath K, Guttman M. 140. Wang J, Syrett CM, Kramer MC, Basu A, Atchison ML, Anguera
The Xist lncRNA exploits three-dimensional genome architecture to MC. Unusual maintenance of X chromosome inactivation predisposes
spread across the X chromosome. Science 2013;341:1237973. female lymphocytes for increased expression from the inactive X. Proc
128. Smeets D, Markaki Y, Schmid VJ, Kraus F, Tattermusch A, Cerase A, Natl Acad Sci U S A 2016;113:E2029-38.

14 Journal of Translational Genetics and Genomics ¦ Volume 1 ¦ November 16, 2017