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Page 8 of 40                         Maner et al. J Cancer Metastasis Treat 2020;6:37  I  http://dx.doi.org/10.20517/2394-4722.2020.60












































                     Figure 3. mTORC1 and two signaling pathways. This figure describes the transcriptional mTORC1 and mTORC2 pathways





































               Figure 4. Crosstalk with SHH pathway: this image describes the crosstalk between multiple pathways. SHH: sonic hedgehog; SMO:
               smoothened; TGF: transforming growth factor
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