Page 226 - Read Online
P. 226
Page 10 of 10 Grelet et al. J Cancer Metastasis Treat 2019;5:16 I http://dx.doi.org/10.20517/2394-4722.2018.85
dissemination. NPJ Breast Cancer 2017;3:21.
43. Olsen JR, Oyan AM, Rostad K, Hellem MR, Liu J, et al. p63 attenuates epithelial to mesenchymal potential in an experimental prostate cell
model. PLoS One 2013;8:e62547.
44. Hwang CK, Wagley Y, Law PY, Wei LN, Loh HH. Phosphorylation of poly(rC) binding protein 1 (PCBP1) contributes to stabilization of
mu opioid receptor (MOR) mRNA via interaction with AU-rich element RNA-binding protein 1 (AUF1) and poly A binding protein (PABP).
Gene 2017;598:113-30.
45. Tian B, Manley JL. Alternative polyadenylation of mRNA precursors. Nat Rev Mol Cell Biol 2017;18:18-30.
46. Wang Z, Day N, Trifillis P, Kiledjian M. An mRNA stability complex functions with Poly(A)-binding protein to stabilize mRNA in vitro.
Mol Cell Biol 1999;19:4552-60.
47. Jenal M, Elkon R, Loayza-Puch F, van Haaften G, Kühn U, et al. The Poly(A)-binding protein nuclear 1 suppresses alternative cleavage and
polyadenylation sites. Cell 2012;149:538-53.
48. Grelet S, Andries V, Polette M, Gilles C, Staes K, et al. The human NANOS3 gene contributes to lung tumour invasion by inducing
epithelial-mesenchymal transition. J Pathol 2015;23:25-37.
49. Grelet S, McShane A, Geslain R, Howe PH. Pleiotropic roles of non-coding RNAs in TGF-β-mediated epithelial-mesenchymal transition
and their functions in tumor progression. Cancers 2017;9:E75.
50. Wang H, Vardy LA, Tan CP, Loo JM, Guo K, et al. PCBP1 suppresses the translation of metastasis-associated PRL-3 phosphatase. Cancer
Cell 2010;18:52-62.
51. Waerner T, Alacakaptan M, Tamir I, Oberauer R, Gal A, et al. ILEI: a cytokine essential for EMT, tumor formation, and late events in
metastasis in epithelial cells. Cancer Cell 2006;10:227-39.
52. Cursons J, Pillman KA, Scheer KG, Gregory PA, Foroutan M, et al. Combinatorial targeting by MicroRNAs Co-ordinates post-
transcriptional control of EMT. Cell Syst 2018;7:77-91.e7.
53. Hussey GS, Link LA, Brown AS, Howley BV, Chaudhury A, et al. Establishment of a TGFβ-induced post-transcriptional EMT gene
signature. PLoS One 2012;7:e52624.
54. Prunier C, Howe PH. Disabled-2 (Dab2) is required for transforming growth factor beta-induced epithelial to mesenchymal transition (EMT).
J Biol Chem 2005;280:17540-8.
55. Song Q, Sheng W, Zhang X, Jiao S, Li F. ILEI drives epithelial to mesenchymal transition and metastatic progression in the lung cancer cell
line A549. Tumour Biol 2014;35:1377-82.
56. Wells SE, Hillner PE, Vale RD, Sachs AB. Circularization of mRNA by eukaryotic translation initiation factors. Mol Cell 1998;2:135-40.
57. Wang ET, Sandberg R, Luo S, Khrebtukova I, Zhang L, et al. Alternative isoform regulation in human tissue transcriptomes. Nature
2008;456:470-6.
58. Paronetto MP, Passacantilli I, Sette C. Alternative splicing and cell survival: from tissue homeostasis to disease. Cell Death Differ
2016;23:1919-29.
59. Singh RK, Cooper TA. Pre-mRNA splicing in disease and therapeutics. Trends Mol Med 2012;18:472-82.
60. Song X, Zeng Z, Wei H, Wang Z. Alternative splicing in cancers: from aberrant regulation to new therapeutics. Semin Cell Dev Biol
2018;75:13-22.
61. Xiong HY, Alipanahi B, Lee LJ, Bretschneider H, Merico D, et al. RNA splicing. The human splicing code reveals new insights into the
genetic determinants of disease. Science 2015;347:1254806.
62. Zhang T, Huang XH, Dong L, Hu D, Ge C, et al. PCBP-1 regulates alternative splicing of the CD44 gene and inhibits invasion in human
hepatoma cell line HepG2 cells. Mol Cancer 2010;9:72.
63. Brown RL, Reinke LM, Damerow MS, Perez D, Chodosh LA, et al. CD44 splice isoform switching in human and mouse epithelium is
essential for epithelial-mesenchymal transition and breast cancer progression. J Clin Invest 2011;121:1064-74.
64. Akker SA, Misra S, Aslam S, Morgan EL, Smith PJ, et al. Pre-spliceosomal binding of U1 small nuclear ribonucleoprotein (RNP) and
heterogenous nuclear RNP E1 is associated with suppression of a growth hormone receptor pseudoexon. Mol Endocrinol Baltim Md
2007;21:2529-40.
65. Brabletz S, Brabletz T. The ZEB/miR-200 feedback loop - a motor of cellular plasticity in development and cancer? EMBO Rep
2010;11:670-7.
66. Lu M, Jolly MK, Levine H, Onuchic JN, Ben-Jacob E. MicroRNA-based regulation of epithelial-hybrid-mesenchymal fate determination.
Proc Natl Acad Sci U S A 2013;110:18144-9.
67. Link LA, Howley BV, Hussey GS, Howe PH. PCBP1/HNRNP E1 protects chromosomal integrity by translational regulation of CDC27.
Mol Cancer Res 2016;14:634-46.