Page 1010 - Read Online

Agbo et al. J Cancer Metastasis Treat 2019;5:x I http://dx.doi.org/10.20517/2394-4722.2019.35 Page 11 of 11

31. Koopmansch B, Berx G, Foidart JM, Gilles C, Winkler R. Interplay between KLF4 and ZEB2/SIP1 in the regulation of E-cadherin
expression. Biochem Biophys Res Commun 2013;431:652-7.
32. Mistry DS, Chen Y, Wang Y, Zhang K, Sen GL. SNAI2 controls the undifferentiated state of human epidermal progenitor cells. Stem
Cells 2014;32:3209-18.
33. Zhu Z, Yu Z, Wang J, Zhou L, Zhang J, et al. Kruppel-like factor 4 inhibits pancreatic cancer epithelial-to-mesenchymal transition and
metastasis by down-regulating caveolin-1 expression. Cell Physiol Biochem 2018;46:238-52.
34. Pinho AV, Rooman I, Real FX. p53-dependent regulation of growth, epithelial-mesenchymal transition and stemness in normal
pancreatic epithelial cells. Cell Cycle 2011;10:1312-21.
35. Sureban SM, May R, Qu D, Weygant N, Chandrakesan P, et al. DCLK1 regulates pluripotency and angiogenic factors via microRNA-
dependent mechanisms in pancreatic cancer. PLoS One 2013;8:e73940.
36. Chen Z, Wang Y, Liu W, Zhao G, Lee S, et al. Doxycycline inducible Kruppel-like factor 4 lentiviral vector mediates mesenchymal to
epithelial transition in ovarian cancer cells. PLoS One 2014;9:e105331.
37. Dong P, Kaneuchi M, Watari H, Hamada J, Sudo S, et al. MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial
cancer cells by targeting oncogene BMI-1. Mol Cancer 2011;10:99.
38. Wu A, Luo W, Zhang Q, Yang Z, Zhang G, et al. Aldehyde dehydrogenase 1, a functional marker for identifying cancer stem cells in
human nasopharyngeal carcinoma. Cancer Lett 2013;330:181-9.
39. Ren D, Wang M, Guo W, Zhao X, Tu X, et al. Wild-type p53 suppresses the epithelial-mesenchymal transition and stemness in PC-3
prostate cancer cells by modulating miR145. Int J Oncol 2013;42:1473-81.
40. Kumar M, Allison DF, Baranova NN, Wamsley JJ, Katz AJ, et al. NF-kappaB regulates mesenchymal transition for the induction of
non-small cell lung cancer initiating cells. PLoS One 2013;8:e68597.
41. Yori JL, Johnson E, Zhou G, Jain MK, Keri RA. Kruppel-like factor 4 inhibits epithelial-to-mesenchymal transition through
regulation of E-cadherin gene expression. J Biol Chem 2010;285:16854-63.
42. Delp EE, Swamynathan S, Kao WW, Swamynathan SK. Spatiotemporally regulated ablation of Klf4 in adult mouse corneal epithelial
cells results in altered epithelial cell identity and disrupted homeostasis. Invest Ophthalmol Vis Sci 2015;56:3549-58.
43. Tiwari A, Loughner CL, Swamynathan S, Swamynathan SK. KLF4 plays an essential role in corneal epithelial homeostasis by
promoting epithelial cell fate and suppressing epithelial-mesenchymal transition. Invest Ophthalmol Vis Sci 2017;58:2785-95.
44. Tiwari A, Swamynathan S, Alexander N, Gnalian J, Tian S, et al. KLF4 regulates corneal epithelial cell cycle progression by
suppressing canonical TGF-beta signaling and upregulating CDK inhibitors P16 and P27. Invest Ophthalmol Vis Sci 2019;60:731-40.
45. Fujimoto S, Hayashi R, Hara S, Sasamoto Y, Harrington J, et al. KLF4 prevents epithelial to mesenchymal transition in human corneal
epithelial cells via endogenous TGF-beta2 suppression. Regen Ther 2019;11:249-57.