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option and stage of disease, and physical activity were 5. Vignali A, De Nardi P. Multidisciplinary treatment of rectal cancer in
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important predictive factors of QOL. The presence of 6. Bowling A. Measuring disease: a review of disease-specific quality of
a modifiable factor is an opportunity for interventional life measurement scales. England: Open University Press; 2001.
strategies to improve the QOL via physical activity 7. Marventano S, Forjaz M, Grosso G, Mistretta A, Giorgianni G, Platania
modification. Organised screening is recommended to A, Gangi S, Basile F, Biondi A. Health related quality of life in colorectal
improve the stage at presentation and concordance cancer patients: state of the art. BMC Surg 2013;13 Suppl 2:S15.
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quality of life in patients undergoing abdominoperineal extirpation or
DECLARATIONS 9. anterior resection for rectal cancer. Ann Surg 2001;233:149-56.
Li X, Song X, Chen Z, Li M, Lu L, Xu Y, Zhan W, He Y, Xu K.
Quality of life in rectal cancer patients after radical surgery: a survey
Authors’ contributions of Chinese patients. World J Surg Oncol 2014;12:161.
Involved in design of the protocol of the study and all 10. Engel J, Kerr J, Schlesinger-Raab A, Eckel R, Sauer H, Hölzel D.
drafts of the manuscript, and reviewed and agreed the Quality of life in rectal cancer patients: a four-year prospective study.
final draft of the manuscript: N. Aminisani, M. Fatemi, Ann Surg 2003;238:203-13.
P. Sarbakhsh, A. Nikanfar, A. Eftekharsadat, E. Jafari 11. Ministry of Health and Medical Education. Cancer office. Cancer
registration country reports 2009. Iran, 2012. Available in Persian
Did data collection and analysis: M. Fatemi, E. Jafari from: crc.tums.ac.ir. [Last accessed on 26 September 2017]
Supervised and supported data collection: N. 12. Nikbakht HA, Aminisani N, Asghari-Jafarabadi M, Hosseini SR.
Aminisani, A. Nikanfar, A. Eftekharsadat Trends in the incidence of colorectal cancer and epidemiologic and
Supervised the data analysis: N. Aminisani, P. clinical characteristics of survivors in babol city in 2007-2012. J
Sarbakhsh Babol Univ Med Sci 2015;17:7-14.
13. Ali Nikbakht H, Aminisani N, Asghari Jafarabadi M, Hosseini SR.
Financial support and sponsorship Quality of life and its determinants among colorectal cancer survivors.
J Kermanshah Univ Med Sci 2015;19:84-92.
This study was funded by the Haematology and 14. Tsunoda A, Nakao K, Watanabe M, Matsui N, Tsunoda Y. Health-
Oncology Research Centre and Centre for Training and related quality of life in patients with colorectal cancer who
Research on Health Management of Tabriz University receive oral uracil and tegafur plus leucovorin. Jpn J Clin Oncol
of Medical Sciences. 2010;40:412-9.
15. Nicolussi AC, Sawada NO. Quality of life of patients with colorectal
Conflicts of interest cancer who were receiving complementary therapy. Acta Paulista de
There are no conflicts of interest. Enfermagem 2009;22:155-61.
16. Akhondi-Meybodi M, Akhondi-Meybodi S, Vakili M, Javaheri
Patient consent Z. Quality of life in patients with colorectal cancer in Iran. Arab J
Gastroenterol 2016;17:127-30.
At the beginning of the study, informed consent was 17. Momeni M, Ghanbari A, Jokar F, Rahimi A, Leyli EK. Predictors
obtained in written from all of the participants. of quality of life in patients with colorectal cancer in Iran. Indian J
Cancer 2014;51:550-6.
Ethics approval 18. Zając O, Spychała A, Murawa D, Wasiewicz J, Foltyn P, Połom K.
The study was conducted in accordance with the Quality of life assessment in patients with a stoma due to rectal cancer.
declaration of Helsinki and had ethics approval from Rep Pract Oncol Radiother 2008;13:130-4.
the Tabriz University of Medical Science Ethical 19. Schmidt CE, Bestmann B, Küchler T, Longo WE, Kremer B. Ten-year
Review Committee (Ethical ID numbers: TBZMED. historic cohort of quality of life and sexuality in patients with rectal
REC.5/4/11460). cancer. Dis Colon Rectum 2005;48:483-92.
20. Rauch P, Miny J, Conroy T, Neyton L, Guillemin F. Quality of
life among disease-free survivors of rectal cancer. J Clin Oncol
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