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Malik et al. J Cancer Metastasis Treat 2017;3:111-5 Journal of
DOI: 10.20517/2394-4722.2017.12
Cancer Metastasis and Treatment

www.jcmtjournal.com
Case Report Open Access

Report of primary leiomyosarcoma of renal

pelvis and literature review

Abhidha Malik , Ritesh Kumar , Abhishek Shankar , Sunil Chumber , Sameer Bakhshi , Seema Kaushal ,
1
3
4
1
2
1
Bala Thirunavukkarasu 4
1 Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi 110029, India.
2 Department of Surgery, All India Institute of Medical Sciences, New Delhi 110029, India.
3 Department of Medical Oncology, All India Institute of Medical Sciences, New Delhi 110029, India.
4 Department of Pathology, All India Institute of Medical Sciences, New Delhi 110029, India.
Correspondence to: Dr. Abhidha Malik, Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi 110029, India.
E-mail: dr.abhidha@gmail.com
How to cite this article: Malik A, Kumar R, Shankar A, Chumber S, Bakhshi S, Kaushal S, Thirunavukkarasu B. Report of primary leiomyosarcoma
of renal pelvis and literature review. J Cancer Metastasis Treat 2017;3:111-5.
ABSTRACT
Article history: Primary sarcomas of kidney are exceptionally rare tumors, accounting for only 1-2% of
Received: 05-02-2017 all malignant tumors of kidney. Leiomyosarcoma (LMS) is the most common histological
Accepted: 24-03-2017 subtype among all renal sarcomas. The authors describe here a case of primary
Published: 30-06-2017 leiomyosarcoma of renal pelvis in a 50-year-old lady, presenting with flank pain. Based
on triple phase cardio-electroencephalographic covariance tracing abdomen, presumptive
Key words: diagnosis of renal cell carcinoma/renal sarcoma/neurogenic tumor was made and patient
Primary, underwent radical nephrectomy. Microscopy reflected spindle cell tumor which showed
leiomyosarcoma, strong positivity for desmin and smooth muscle actin with negative epithelial markers,
renal pelvis
thereby confirming the diagnosis of renal LMS. Owing to aggressive nature and low
survival rates of LMS patient received adjuvant treatment in form of chemotherapy and
radiotherapy. Patient is doing well 1 year post treatment.

INTRODUCTION a case of a 50-year-old lady with leiomyosarcoma
originating in renal pelvis along with relevant review
Primary sarcomas of kidney constitute 1-2% of all of literature.
malignant tumors of kidney. LMS is most common
[1]
histological subtype, accounting 60-70% of all CASE REPORT
sarcomas of kidney, commonly seen in females in
4th-6th decades. Radical nephrectomy remains the A 50-year-old postmenopausal lady, known case of
[2]
treatment of choice. The role of adjuvant treatment hypothyroidism on T Thyroxin for 3 years, presented
[3]
remains debatable due to paucity of data on with diffuse dull aching paroxysmal pain in left flank
treatment of this rare neoplasm. Herein, we report of 2 months duration. On physical examination PORT

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