Page 116 - Read Online

were extremely similar (9% and 11%, respectively). 11. Garrison JE, Kasdon DL. Intramedullary spinal teratoma:
Many authors no longer recommend radical resection as case report and review of the literature. Neurosurgery
a preferred management policy for all cases, [19,20] since 1980;7:509-12.
the rate of adherence to the cord reaches 50% in this 12. Padovani R, Tognetti F, Laudadio S, Manetto V. Teratoid cyst
of the spinal cord. Neurosurgery 1983;13:74-7.
region, and any attempt at total resection may result in 13. Pelissou-Guyotat I, Sindou M, Pialat J, Goutelle A.
[10]
inadvertent damage to the conus. In the present case, Intramedullary mature teratoma associated with an attached
complete resection was not feasible without potential cord and an intradural lipoma. Apropos of a surgically treated
injury of the conus medullaris, so it was judged safer to case. Review of the literature. Neurochirurgie 1988;34:205-9.
realize a gross total resection in order to preserve nerve 14. Nicoletti GF, Passanisi M, Platania N, Lanzafame S,
integrity. Albanese V. Intramedullary spinal cystic teratoma of the
conusmedullaris with caudal exophytic development: case
Due to the extremely low incidence of adult mature report. Surg Neurol 1994;41:106-11.
spinal teratoma and limited knowledge of this disease, 15. Caruso R, Antonelli M, Cervoni L, Salvati M. Intramedullary
there is little evidence to support the use of adjunctive teratoma: case report and review of the literature. Tumori
therapies. Radiation therapy is not justifi ed since 1996;82:616-20.
[36]
mature teratomas are benign tumors, and the effi cacy 16. al-Sarraj ST, Parmar D, Dean AF, Phookun G, Bridges LR.
Clinicopathological study of seven cases of spinal cord teratoma:
[36]
of chemotherapy has not been demonstrated. Given a possible germ cell origin. Histopathology 1998;32:51-6.
the slow-growing nature of these tumors, patients 17. Poeze M, Herpers MJ, Tjandra B, Freling G, Beuls EA.
will require serial clinical and radiological follow-up Intramedullary spinal teratoma presenting with urinary
examinations for several years. Tumor markers such as retention: case report and review of the literature. Neurosurgery
B human chorionic hormone and alpha fetoproteinare 1999;45:379-85.
of little interest in the follow-up of patients operated for 18. Fan X, Turner JE, Turner TM, Elrod JP, Clough JA,
mature intraspinal teratomas since a recurrence can take Howell EI, Johnson MD. Carcinoid tumor development in
place from nonsecreting parts of the tumor. [36] an intramedullary spinal cord mature teratoma. AJNR Am J
Neuroradiol 2001;22:1778-81.
In conclusion, mature intradural teratomas in adults are 19. Nonomura Y, Miyamoto K, Wada E, Hosoe H, Nishimoto H,
rare, with few accompanying spinal anomalies. Their Ogura H, Shimizu K. Intramedullary teratoma of the spine:
report of two adult cases. Spinal Cord 2002;40:40-3.
location in the conus medullaris is exceptional and can 20. Hejazi N, Witzmann A. Spinal intramedullary teratoma with
present with sciatica. Although complete resection is the exophytic components: report of two cases and review of the
primary goal, subtotal removal can be considered as a literature. Neurosurg Rev 2003;26:113-6.
safe and effective option to manage these lesions, with 21. Ak H, Ulu MO, Sar M, Albayram S, Aydin S, Uzan M. Adult
the understanding that a small number of these patients intramedullary mature teratoma of the spinal cord: review
may need reoperation. Long-term follow-up is mandatory. of the literature illustrated with an unusual example. Acta
Neurochir (Wien) 2006;148:663-9.
References 22. Makary R, Wolfson D, Dasilva V, Mohammadi A, Shuja S.
Intramedullary mature teratoma of the cervical spinal cord at
1. Fernández-Cornejo VJ, Martínez-Pérez M, Polo-García LA, C1-2 associated with occult spinal dysraphism in an adult.
Martínez-Lage JF, Poza M. Cystic mature teratoma of the Case report and review of the literature. J Neurosurg Spine
fi lum terminale in an adult. Case report and review of the 2007;6:579-84.
literature. Neurocirugia (Astur) 2004;15:290-3. 23. Biswas A, Puri T, Goyal S, Gupta R, Eesa M, Julka PK, Rath GK.
2. Kubie LS, Fulton JF. A Clinical and Pathological Study of Two Spinal intradural primary germ cell tumour-review of literature
Teratomatous Cysts of the Spinal Cord, Containing Mucous and case report. Acta Neurochir (Wien) 2009;151:277-84.
and Ciliated Cells. Chicago: R.R. Donnelley; 1928. p. 42. 24. Ghostine S, Perry E, Vaynman S, Raghavan R, Tong KA,
3. Hosoi K. Multiple neurofi bromatosis (von Recklinghausen’s Samudrala S, Johnson JP, Colohan A. The rare case of an
disease) with special reference to malignant transformation. intramedullary cervical spinal cord teratoma in an elderly
Arch Surg 1931;22:258-81. adult: case report and literature review. Spine (Phila Pa 1976)
4. Sullivan BH. Intraspinal teratoma, with report of a case. 2009;34:E973-8.
Brooklyn Hosp J 1948;6:142-5. 25. Ijiri K, Hida K, Yano S, Iwasaki Y. Huge intradural ossifi cation
5. Case Reports of the Massachusetts General Hospital; weekly caused by a mature spinal teratoma: case report. Neurosurgery
clinicopathological exercises: case 42502. N Engl J Med 2009;64:1200-1.
1956;255:1153-7. 26. Jian W, Ying W, Chao Y. Intramedullary spinal teratoma of the
6. Sloof JL, Kernohan JW, McCarty CS. Primary Intramedullary conusmedullaris: report of two cases. Acta Neurochir (Wien)
Tumors of the Spinal Cord and Filumterminale. Philadelphia: 2010;152:553-4.
WB Saunders; 1964. p. 134. 27. Musil J, Mrlian A, Duba M, Kren L, Smrcka M. Probably the
7. Rewcastle NB, Francoeur J. Teratomatous cysts of the spinal oldest patient with the diagnosis of medullar conusteratoma.
canal; with “sex chromatin” studies. Arch Neurol 1964;11:91-9. Bratisl Lek Listy 2011;112:357-9.
8. Hansebout RR, Bertrand G. Intraspinalteratoma simulating 28. Li Y, Yang B, Song L, Yan D. Mature teratoma of the spinal
protruded intervertebral disc. J Neurosurg 1965;22:374-9. cord in adults: An unusual case. Oncol Lett 2013;6:942-6.
9. Eneström S, Von Essen C. Spinal teratoma. Acta Neurochir 29. Vanguardia MK, Honeybul S, Robbins P. Subtotal resection
1977;39:121-6. of an intradural mature teratoma in an adult presenting with
10. Rosenbaum TJ, Soule EH, Onofrio BM. Teratomatous cyst of diffi culty initiating micturition. Surg Neurol Int 2014;5:23.
the spinal canal. Case report. J Neurosurg 1978;49:292-7. 30. Bouaziz M, Haouam K, Laouar O, Lankar A. A case of

Journal of Cancer Metastasis and Treatment ¦ Volume 1 ¦ Issue 2 ¦ July 15, 2015 ¦ 109