Page 74 - Read Online

45. Barrett MT, Galipeau PC, Sanchez CA, Emond MJ, Reid BJ. Sougnez C, Onofrio RC, Guiducci C, Beroukhim R, Zhou Z,
Determination of the frequency of loss of heterozygosity in Lin L, Lin J, Reddy R, Chang A, Landrenau R, Pennathur A,
esophageal adenocarcinoma by cell sorting, whole genome Ogino S, Luketich JD, Golub TR, Gabriel SB, Lander ES,
amplifi cation and microsatellite polymorphisms. Oncogene Beer DG, Godfrey TE, Getz G, Bass AJ. Exome and
1996;12:1873-8. whole-genome sequencing of esophageal adenocarcinoma
46. Dunn J, Garde J, Dolan K, Gosney JR, Sutton R, Meltzer SJ, identifi es recurrent driver events and mutational complexity.
Field JK. Multiple target sites of allelic imbalance on Nat Genet 2013;45:478-86.
chromosome 17 in Barrett’s oesophageal cancer. Oncogene 57. Jarzynka MJ, Hu B, Hui KM, Bar-Joseph I, Gu W, Hirose T,
1999;18:987-93. Haney LB, Ravichandran KS, Nishikawa R, Cheng SY.
47. Skacel M, Petras RE, Rybicki LA, Gramlich TL, Richter JE, ELMO1 and Dock180, a bipartite Rac1 guanine nucleotide
Falk GW, Goldblum JR. p53 expression in low grade exchange factor, promote human glioma cell invasion. Cancer
dysplasia in Barrett’s esophagus: correlation with interobserver Res 2007;67:7203-11.
agreement and disease progression. Am J Gastroenterol 58. Nones K, Waddell N, Wayte N, Patch AM, Bailey P, Newell F,
2002;97:2508-13. Holmes O, Fink JL, Quinn MC, Tang YH, Lampe G, Quek K,
48. Chung SM, Kao J, Hyjek E, Chen YT. p53 in esophageal Loffl er KA, Manning S, Idrisoglu S, Miller D, Xu Q,
adenocarcinoma: a critical reassessment of mutation frequency Waddell N, Wilson PJ, Bruxner TJ, Christ AN, Harliwong I,
and identifi cation of 72Arg as the dominant allele. Int J Oncol Nourse C, Nourbakhsh E, Anderson M, Kazakoff S,
2007;31:1351-5. Leonard C, Wood S, Simpson PT, Reid LE, Krause L,
49. Mokrowiecka A, Wierzchniewska-Lawska A, Smolarz B, Hussey DJ, Watson DI, Lord RV, Nancarrow D, Phillips WA,
Romanowicz-Makowska H, Malecka-Panas E. p16 gene Gotley D, Smithers BM, Whiteman DC, Hayward NK,
mutations in Barrett’s esophagus in gastric metaplasia-intestinal Campbell PJ, Pearson JV, Grimmond SM, Barbour AP.
metaplasia-dysplasia-adenocarcinoma sequence. Adv Med Sci Genomic catastrophes frequently arise in esophageal
2012;57:71-6. adenocarcinoma and drive tumorigenesis. Nat Commun
50. Hong J, Resnick M, Behar J, Wang LJ, Wands J, DeLellis RA, 2014;5:5224.
Souza RF, Spechler SJ, Cao W. Acid-induced p16 59. Dvorak K, Payne CM, Chavarria M, Ramsey L, Dvorakova B,
hypermethylation contributes to development of esophageal Bernstein H, Holubec H, Sampliner RE, Guy N, Condon A,
adenocarcinoma via activation of NADPH oxidase NOX5-S. Bernstein C, Green SB, Prasad A, Garewal HS. Bile acids in
Am J Physiol Gastrointest Liver Physiol 2010;299:G697-706. combination with low pH induce oxidative stress and oxidative
51. Wang JS, Guo M, Montgomery EA, Thompson RE, Cosby H, DNA damage: relevance to the pathogenesis of Barrett’s
Hicks L, Wang S, Herman JG, Canto MI. DNA promoter oesophagus. Gut 2007;56:763-71.
hypermethylation of p16 and APC predicts neoplastic 60. Satou K, Hori M, Kawai K, Kasai H, Harashima H, Kamiya H.
progression in Barrett’s esophagus. Am J Gastroenterol Involvement of specialized DNA polymerases in mutagenesis
2009;104:2153-60. by 8-hydroxy-dGTP in human cells. DNA Repair (Amst)
52. Weaver JM, Ross-Innes CS, Shannon N, Lynch AG, 2009;8:637-42.
Forshew T, Barbera M, Murtaza M, Ong CA, Lao-Sirieix P, 61. Xu E, Gu J, Hawk ET, Wang KK, Lai M, Huang M,
Dunning MJ, Smith L, Smith ML, Anderson CL, Carvalho B, Ajani J, Wu X. Genome-wide methylation analysis shows
O’Donovan M, Underwood TJ, May AP, Grehan N, similar patterns in Barrett’s esophagus and esophageal
Hardwick R, Davies J, Oloumi A, Aparicio S, Caldas C, adenocarcinoma. Carcinogenesis 2013;34:2750-6.
Eldridge MD, Edwards PA, Rosenfeld N, Tavare S, 62. Alvarez H, Opalinska J, Zhou L, Sohal D, Fazzari MJ,
Fitzgerald RC, Consortium O. Ordering of mutations in Yu Y, Montagna C, Montgomery EA, Canto M, Dunbar KB,
preinvasive disease stages of esophageal carcinogenesis. Nat Wang J, Roa JC, Mo Y, Bhagat T, Ramesh KH, Cannizzaro L,
Genet 2014;46:837-43. Mollenhauer J, Thompson RF, Suzuki M, Meltzer SJ,
53. Streppel MM, Lata S, DelaBastide M, Montgomery EA, Melnick A, Greally JM, Maitra A, Verma A. Widespread
Wang JS, Canto MI, Macgregor-Das AM, Pai S, Morsink FH, hypomethylation occurs early and synergizes with gene
Offerhaus GJ, Antoniou E, Maitra A, McCombie WR. amplifi cation during esophageal carcinogenesis. PLoS Genet
Next-generation sequencing of endoscopic biopsies identifi es 2011;7:E1001356.
ARID1A as a tumor-suppressor gene in Barrett’s esophagus. 63. Alvi MA, Liu X, O’Donovan M, Newton R, Wernisch L,
Oncogene 2014;33:347-57. Shannon NB, Shariff K, di Pietro M, Bergman JJ,
54. Zang ZJ, Cutcutache I, Poon SL, Zhang SL, McPherson JR, Ragunath K, Fitzgerald RC. DNA methylation as an adjunct
Tao J, Rajasegaran V, Heng HL, Deng N, Gan A, Lim KH, to histopathology to detect prevalent, inconspicuous dysplasia
Ong CK, Huang D, Chin SY, Tan IB, Ng CC, Yu W, Wu Y, and early-stage neoplasia in Barrett’s esophagus. Clin Cancer
Lee M, Wu J, Poh D, Wan WK, Rha SY, So J, Salto-Tellez M, Res 2013;19:878-88.
Yeoh KG, Wong WK, Zhu YJ, Futreal PA, Pang B, Ruan Y, 64. Kaz AM, Grady WM, Stachler MD, Bass AJ. Genetic
Hillmer AM, Bertrand D, Nagarajan N, Rozen S, Teh BT, and epigenetic alterations in barrett’s esophagus and
Tan P. Exome sequencing of gastric adenocarcinoma identifi es esophageal adenocarcinoma. Gastroenterol Clin North Am
recurrent somatic mutations in cell adhesion and chromatin 2015;44:473-89.
remodeling genes. Nat Genet 2012;44:570-4. 65. Eads CA, Lord RV, Kurumboor SK, Wickramasinghe K,
55. Wiegand KC, Sy K, Kalloger SE, Li-Chang H, Woods R, Skinner ML, Long TI, Peters JH, DeMeester TR,
Kumar A, Streutker CJ, Hafezi-Bakhtiari S, Zhou C, Lim HJ, Danenberg KD, Danenberg PV, Laird PW, Skinner KA.
Huntsman DG, Clarke B, Schaeffer DF. ARID1A/BAF250a Fields of aberrant CpG island hypermethylation in Barrett’s
as a prognostic marker for gastric carcinoma: a study of 2 esophagus and associated adenocarcinoma. Cancer Res
cohorts. Hum Pathol 2014;45:1258-68. 2000;60:5021-6.
56. Dulak AM, Stojanov P, Peng S, Lawrence MS, Fox C, 66. Wong DJ, Paulson TG, Prevo LJ, Galipeau PC, Longton G,
Stewart C, Bandla S, Imamura Y, Schumacher SE, Shefl er E, Blount PL, Reid BJ. p16(INK4a) lesions are common, early
McKenna A, Carter SL, Cibulskis K, Sivachenko A, abnormalities that undergo clonal expansion in Barrett’s
Saksena G, Voet D, Ramos AH, Auclair D, Thompson K, metaplastic epithelium. Cancer Res 2001;61:8284-9.

128 Journal of Cancer Metastasis and Treatment ¦ Volume 1 ¦ Issue 3 ¦ October 15, 2015 ¦