Page 35 - Read Online
P. 35

Page 14 of 17                       Wenner et al. J Cancer Metastasis Treat 2020;6:33  I  http://dx.doi.org/10.20517/2394-4722.2020.73

               Authors’ contributions
               Responsible for compiling information along with the tables related to PEITC, capsaicin, withaferin A and
               genistein A: Wenner C, Stewart R, McCabe A, Pepe J, Oberlin J
               Helped with the figures and future perspectives section: VanWert A
               Conceived the idea and compiled information related to introduction, limitations to phytochemicals and
               future perspectives & conclusions and was responsible for the preparation of the final article: Bommareddy A

               Availability of data and materials
               Not applicable.


               Financial support and sponsorship
               Not applicable.

               Conflicts of interest
               All authors declared that there are no conflicts of interest.


               Ethical approval and consent to participate
               Not applicable.


               Consent for publication
               Not applicable.


               Copyright
               © The Author(s) 2020.


               REFERENCES
               1.   Yorimitsu T, Klionsky DJ. Autophagy: molecular machinery for self-eating. Cell Death Differ 2005;12 Suppl 2:1542-52.
               2.   Levy JMM, Towers CG, Thorburn A. Targeting autophagy in cancer. Nat Rev Cancer 2017;17:528-42.
               3.   Mizushima N, Komatsu M. Autophagy: renovation of cells and tissues. Cell 2011;147:728-41.
               4.   Amaravadi R, Kimmelman AC, White E. Recent insights into the function of autophagy in cancer. Genes Dev 2016;30:1913-30.
               5.   Dikic I, Elazar Z. Mechanism and medical implications of mammalian autophagy. Nat Rev Mol Cell Biol 2018;19:349-64.
               6.   Nicklin P, Bergman P, Zhang B, Triantafellow E, Wang H, et al. Bidirectional transport of amino acids regulates mTOR and autophagy.
                   Cell 2009;136:521-34.
               7.   Dong JY, Qin LQ. Soy isoflavones consumption and risk of breast cancer incidence or recurrence: a meta-analysis of prospective studies.
                   Breast Cancer Res Treat 2011;125:315-23.
               8.   Liu X, Lv K. Cruciferous vegetables intake is inversely associated with risk of breast cancer: a meta-analysis. Breast 2013;22:309-13.
               9.   Li Y, Li S, Meng X, Gan RY, Zhang JJ, et al. Dietary natural products for prevention and treatment of breast cancer. Nutrients 2017;9:728.
               10.  Moosavi MA, Haghi A, Rahmati M, Taniguchi H, Mocan A, et al. Phytochemicals as potent modulators of autophagy for cancer therapy.
                   Cancer Lett 2018;424:46-69.
               11.  Deng S, Shanmugam MK, Kumar AP, Yap CT, Sethi G, et al. Targeting autophagy using natural compounds for cancer prevention and
                   therapy. Cancer 2019;125:1228-46.
               12.  Patra S, Mishra SR, Behera BP, Mahapatra KK, Panigrahi DP, et al. Autophagy-modulating phytochemicals in cancer therapeutics:
                   current evidences and future perspectives. Semin Cancer Biol 2020; doi: 10.1016/j.semcancer.2020.05.008.
               13.  Gupta P, Wright SE, Kim SH, Srivastava SK. Phenethyl isothiocyanate: a comprehensive review of anti-cancer mechanisms. Biochim
                   Biophys Acta 2014;1846:405-24.
               14.  Yu C, Gong AY, Chen D, Solelo Leon D, Young CY, et al. Phenethyl isothiocyanate inhibits androgen receptor-regulated transcriptional
                   activity in prostate cancer cells through suppressing PCAF. Mol Nutr Food Res 2013;57:1825-33.
               15.  Horoszewics JS, Leong SS, Kawinski E, Karr JP, Rosenthal H, et al. LNCaP model of human prostatic carcinoma. Cancer Res
                   1983;43:1809-18.
               16.  Pustylnikov S, Costabile F, Beghi S, Facciabene A. Targeting mitochondria in cancer: current concepts and immunotherapy approaches.
                   Transl Res 2018;202:35-51.
               17.  Bommareddy A, Hahm ER, Xiao D, Powolny AA, Fisher AL, et al. Atg5 regulates phenethyl isothiocyanate-induced autophagic and
                   apoptotic cell death in human prostate cancer cells. Cancer Res 2009;69:3704-12.
               18.  Powolny AA, Bommareddy A, Hahm ER, Normolle DP, Beumer JH, et al. Chemopreventative potential of the cruciferous vegetable
   30   31   32   33   34   35   36   37   38   39   40