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Figure 1. Result of multicolor banding (MCB) probesets for chromosomes 4, 7 and 10 are shown. MCB 10 showed the founder clone and
subclone. Locus-specific probes (LSPs) for chromosomes 2, 7 and 10 characterized the breakpoints in 2q37.3, 7p34, 10q24.3 and 10q25.1
[Table 1]. The final karyotype after application of all approaches is summarized in the text. der = derivative chromosome
In the FISH-studies done here, between 15 and 25 metaphases were evaluated per applied probe-set, thus in
the final karyotype overall percentages are given for the observed clones.
