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Mantovani et al. Hepatoma Res 2020;6:78  I  http://dx.doi.org/10.20517/2394-5079.2020.75                                    Page 5 of 22

                Afolabi et al. [35]  80 Nigerian patients with T2DM recruited from the endocrinology clinic of a   Prevalence of NAFLD on
                                hospital                                                US was 68.8%
                                                           2
                                Mean age 61 years, mean BMI 26 kg/m , 38% males
                Moh Moh et al. [36]  172 South Korean patients with T2DM who were admitted for glucose control to  Prevalence of NAFLD on
                                the endocrinology division of a university hospital     US was 51%
                                                           2
                                Mean age 57 years, mean BMI 25 kg/m , 50% males
                Cosma et al. [37]  60 Italian patients with T2DM enrolled in the study during their routine visit at a  Prevalence of NAFLD on
                                diabetes Centre                                         US was 88%
                                Mean age 65 years, BMI 32 kg/m , 42% males
                                                       2
                Almobarak et al. [38]  167 Sudanese patients with T2DM recruited from the outpatient of a diabetic   Prevalence of NAFLD on
                                center                                                  US was 50.3%
                                87% subjects were aged 40-70 years, 8% subjects > 70 years and 5% subjects
                                < 40 years, mean 46.7% males
                Yan et al. [39]  212 Chinese patients with T2DM recruited from a metabolic disease hospital  Prevalence of NAFLD on
                                                           2
                                Mean age 54 years, mean BMI 27 kg/m , 57% males         US was 67.5%
                Alsabaani et al. [40]  245 Arab patients with T2DM recruited from primary healthcare centers  Prevalence of NAFLD on
                                Mean age 57 years, 66% males                            US was 72.8%
                Gutierrez-Buey et al. [41]  56 Spanish patients with well-controlled T2DM (HbAc1 < 7%)  Prevalence of NAFLD on
                                                           2
                                Mean age 64 years, mean BMI 28 kg/m , 80% males         US or CT was 73.2%
                Zawdie et al. [42]  96 Ethiopian patients with T2DM attending a diabetic clinic  Prevalence of NAFLD on
                                Mean BMI 23 kg/m , 47% males                            US was 73%
                                              2
                Dvorak et al. [43]  180 Czech patients with T2DM                        Prevalence of NAFLD on
                                Mean age 64 years, mean BMI 32 kg/m , 63% males         US was 79%
                                                           2
                Hua et al. [44]  1,037 Chinese patients with T2DM who visited for different medical reasons a   Prevalence of NAFLD on
                                specific hospital in the city of Nanjing were enrolled  US was 56.3%
                                                           2
                                Mean age 57 years, mean BMI 24 kg/m , 59% males
                Mantovani et al. [45]  222 Italian patients with T2DM, who regularly attended a specific diabetes clinic Prevalence of NAFLD on
                                                           2
                                Mean age 67 years, mean BMI 29 kg/m , 70% males         US was 71.2%
                Olusanya et al. [46]  168 Nigerian patients with T2DM evaluated at an endocrine clinic  Prevalence of NAFLD on
                                                           2
                                Mean age 53 years, mean BMI 28 kg/m , 35% males         US was 16.7%
                Chang et al. [47]  97 Chinese patients with T2DM who agreed to participate in the study  Prevalence of NAFLD on
                                                           2
                                Mean age 47 years, mean BMI 26 kg/m , 71% males         US was 69%
                Zhao et al. [48]  2,042 Chinese patients with T2DM hospitalized in an endocrinology and   Prevalence of NAFLD on
                                metabolism department                                   US was 40.2%
                                                           2
                                Mean age 60 years, mean BMI 25 kg/m , 47% males
                Zhang et al. [49]  175 Chinese patients with newly diagnosed T2DM enrolled in this study from the  Prevalence of NAFLD on
                                endocrinology department of a hospital in Wuhan         US was 53%
                                                           2
                                Mean age 52 years, mean BMI 24 kg/m , 56% males
                Johansen et al. [50]  120 Danish patients with T2DM recruited at the diabetes outpatient clinic at a   Prevalence of NAFLD on
                                university hospital                                     MRI was 48 %
                                                           2
                                Mean age 63 years, mean BMI 30 kg/m , 73% males
                Fan et al. [51]  541 Chinese patients with T2DM recruited from a department of endocrinology   Prevalence of NAFLD on
                                and metabolism                                          US was 56.6%
                                                           2
                                Mean age 58 years, mean BMI 25 kg/m , 50% Males
                García Díaz et al. [52]  58 Spanish patients with T2DM whose diabetes was treated in any medical   Prevalence of NAFLD on
                                center of Lanzarote                                     US was 57.8%
                                                           2
                                Mean age 55 years, mean BMI 31 kg/m , 61% males
                Demir et al. [53]  124 Turkish patients with T2DM invited to undergo a liver US for screening  Prevalence of NAFLD on
                                                           2
                                Mean age 53 years, mean BMI 33 kg/m , 37% males         US was 94.3%
                Petit et al. [54]  308 French patients screened at an endocrinology department to participate   Prevalence of NAFLD on
                                in the study to determine whether a specific polymorphism was involved in the   MRI was 65.2%
                                development of NAFLD
                                                           2
                                Mean age 60 years, mean BMI 34 kg/m , 51% males
                Zhao et al. [55]  629 Chinese patients with T2DM enrolled to evaluate their liver conditions  Prevalence of NAFLD on
                                Mean age 44 years, mean BMI 26 kg/m , 91% males         US was 67.7%
                                                           2
                Mantovani et al. [56]  330 Italian patients with T2DM                   Prevalence of NAFLD on
                                who regularly attended a diabetes clinic and            US was 72.1%
                                had undergone a first 24-hour Holter monitoring for clinical reasons
                                                           2
                                Mean age 70 years, mean BMI 29 kg/m , 65% males
                Barchetta et al. [57]  62 Italian patients with T2DM referred to diabetes outpatient clinics who   Prevalence of NAFLD on
                                underwent clinical work-up                              MRI was 56.5%
                                                           2
                                Mean age 59 years, mean BMI 30 kg/m , 72% males
                Choe et al. [58]  5,507 South Korean patients with T2DM diagnosed at the Huh’s Diabetes   Prevalence of NAFLD on
                                Center in Seoul, who underwent an abdominal US          US was 46.4%
                                                           2
                                Mean age 57 years, mean BMI 24 kg/m , 51% males
                Silaghi et al. [59]  336 Romanian patients with T2DM who regularly attended diabetes evaluation   Prevalence of NAFLD on
                                in the same clinic                                      US was 86%
                                Mean age 56 years, mean BMI 32 kg/m 2
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