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Page 4 of 22 Mantovani et al. Hepatoma Res 2020;6:78 I http://dx.doi.org/10.20517/2394-5079.2020.75

Table 1. Principal studies evaluating the prevalence of NAFLD in patients with type 2 diabetes mellitus published in the last
five years
Author Characteristics of study Results
Portillo-Sanchez et al. [12] 103 patients with T2DM from USA recruited from responses to local newspaper Prevalence of NAFLD on
advertisements or from people attending clinics in various USA medical Centers MRI was 50%
2
Mean age: 60 years; mean BMI: 33 kg/m ; 87% males
Kwok et al. [13] 1,918 patients with T2DM from Hong Kong, who attended diabetic complications Prevalence of NAFLD on
screening US was 73%
2
Mean age 60 years; mean BMI 33 kg/m ; 87% males
Arab et al. [14] 133 Chilean patients with T2DM invited by diabetologists and family physicians Prevalence of NAFLD on
for liver disease surveillance assessment MRI was 64%
2
Mean age 60 years; mean BMI 30 kg/m , 47% males
Jung et al. [15] 186 South Korean patients with T2DM admitted to the Endocrinology Division of Prevalence of NAFLD on
a university hospital US was 53%
2
Mean age 58 years; mean BMI 25 kg/m ; 30% Males
Masarone et al. [16] 63 Italian patients with T2DM admitted to a tertiary center of internal medicine Prevalence of NAFLD on
and hepatology liver biopsy was 100%
2
Mean age 57 years, mean BMI 34.4 kg/m , 52.3% males
Petit et al. [17] 264 French patients with T2DM screened prospectively at an endocrinology Prevalence of NAFLD on
department MRI was 63%
2
Mean age 60 years, mean BMI 34 kg/m , 49% males
Wilman HR et al. [18] 226 British patients with T2DM who provided written informed consent to the Prevalence of NAFLD on
study in the United Kingdom Biobank imaging enhancement MRI was 50%
Doycheva et al. [19] 100 patients with T2DM from USA recruited via newspaper advertisement and Prevalence of NAFLD on
from primary care practices MRI was 65%
2
Mean age 60 years, mean BMI 31 kg/m , 53% males
Ding et al. [20] 1,648 Chinese patients with T2DM who lived in a specific district of Shangai Prevalence of NAFLD on
2
Mean age 62 years, mean BMI 25 kg/m , 49% males US was 41.6%
Al Rifai et al. [21] 517 patients with T2DM of different ethnicity, from different areas of USA, Prevalence of NAFLD on
without known CVD at the time of enrollment CT was 28.4%
Williams et al. [22] 106 Australian patients with T2DM from a tertiary diabetes center Prevalence of NAFLD on
2
Mean age 63 years, mean BMI 30 kg/m , 61% males US was 84%
Cusi et al. [23] 385 patients with T2DM from USA who had liver fat content evaluated by MRI Prevalence of NAFLD on
in four phase 3 studies of basal insulin peglispro (BIL) MRI was 75.6% in insulin-
2
Mean age 60 years, mean BMI 32 kg/m , 62% males naïve T2DM patients,
61.7% in insulin-treated
T2DM patients
Guo et al. [24] 8,571 Chinese patients with T2DM hospitalized in the department of Prevalence of NAFLD on
endocrinology and metabolism of a hospital in Shangai US was 50.6%
2
Mean age 60 years, mean BMI 25 kg/m , 56% males
Herath et al. [25] 233 Sri Lankan patients with T2DM followed up at a diabetes center Prevalence of NAFLD on
2
Mean age 58 years, mean BMI 25 kg/m , 47% males US was 62.6%
Sberna et al. [26] 179 French patients with T2DM referred to a tertiary diabetes department Prevalence of NAFLD on
Mean age 60 years, mean BMI 34 kg/m , 47% males MRI was 68.7%
2
Krishan et al. [27] 100 Indian patients with T2DM who underwent a routine health check-up Prevalence of NAFLD on
2
Mean age 51 years, mean BMI 28 kg/m , 82% males US was 65%
Su et al. [28] 445 Chinese patients with T2DM who visited the hospital for evaluation or Prevalence of NAFLD on
treatment of T2DM US was 41.4%
2
Mean age 60 years, mean BMI 25 kg/m , 53% males
Vanjiappan et al. [29] 300 Indian patients with T2DM attending the outpatient department of a Prevalence of NAFLD on
tertiary care hospital US was 61%
2
Mean age 54 years, mean BMI 25 kg/m , 54% males
He et al. [30] 331 hospitalized patients from China with T2DM Prevalence of NAFLD on
2
Mean age 57 years, mean BMI 26 kg/m , 50% males US was 63%
Kabir et al. [31] 258 Bangladeshi patients with T2DM included in this observational study in the Prevalence of NAFLD on
department of medicine of a hospital in Bangladesh US was 64.7%
Lai et al. [32] 557 Malaysian patients with T2DM attending the diabetes clinic of a university Prevalence of NAFLD on
hospital US was 72.4%
Mean age 61 years, 41% males
Hashimoto et al. [33] 145 Japanese patients with T2DM recruited from the outpatient clinic of a Prevalence of NAFLD on
university hospital in Kyoto US was 67%
2
Mean age 66 years, mean BMI 25 kg/m , 55 % males
Zou et al. [34] 2646 Chinese patients with T2DM recruited from a local health examination Prevalence of NAFLD on
center for diabetes, newly diagnosed diabetics or with a previous diagnosis of US was 50.9%
T2DM
2
Mean age 61 years, mean BMI 26 kg/m , 42% males