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Figure 1: Kaplan-Meier curve. (a) Curve for reasons (1: hepatits; 2: others); (b) curve for Child-Pugh class (1: class B; 2: class C); (c) curve for alcohol (1: alcoholic; 2:
non alcoholic); (d) curve for PVT (1: present; 2: absent); (e) curve for smoking (1: smokers; 2: non smokers); (f) curve for age (1: > 63 years; 2: < 63 years); (g)
curve for gender (1: female; 2: male). PVT: portal vein thrombosis
At the end of the study, 7 patients were alive and 34 patients Statistical analysis
died. The survival days were calculated till April 2015. The primary outcome was the overall mean survival
which was calculated for all the patients using Kaplan-
Efficacy Meier method. All the statistical analysis was done in
[9]
The efficacy of the drug was based on the changes SPSS software version 16.00. The log-rank analysis was
in laboratory investigations such as haematological used to determine the significance at the confidence
parameters like haemoglobin, platelets, white blood interval was 95%.
cell (WBC) level as after the therapy and liver function
parameters like serum bilirubin, aspartate transaminase RESULTS
(AST), alanine transaminase (ALT), alkaline phosphatase Patient’s characteristics
(ALP) and serum albumin levels which was monitored A total of 50 patients were found to be treated with sorafenib
after the therapy. Adverse drug reactions were collected in our hospital between January 2009 and December 2014.
from the case files. In that, 1 was found to be taken up renal cell carcinoma,
226 Hepatoma Research | Volume 2 | August 5, 2016