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Original Article

Surgical resection or radiofrequency ablation in the

management of hepatocellular carcinoma: single center

experience

1
1
Wael Mansy , Morsi Mohammed , Sameh Saber 2
1 Department of General Surgery, Faculty of Medicine, Zagazig University, Zagazig 44519, Egypt
2 Department of Radiology, Faculty of Medicine, Zagazig University, Zagazig 44519, Egypt

ABSTRACT
Aim: The aim of this study is to prove or disprove the superiority of surgical resections over radiofrequency ablation (RFA)
with respect to efficacy and safety. Methods: The study was conducted in Zagazig University Hospitals, which included 40
patients with hepatocellular carcinoma (HCC) during the period from November 2011 to December 2014, using either liver
resection or RFA. Results: Hepatic resection was done in 20 patients (13 males, 7 females). Interventional RFA was done in
20 patients (12 males, 8 females). There was no in-hospital mortality after resection. One- and two-year survival rates were
85% and 70% respectively. There was no in-hospital mortality after RFA. One- and two-year survival rates were 80% and
65% respectively. Conclusion: Surgical resection is preferred over RFA in HCC-liver cirrhosis Child A patients with tumor
sizes ≥ 3 cm. HCC-liver cirrhosis Child A patients with masses < 3 cm have almost the same results with both surgery and
RFA. But in special cases such as central position lesions, RFA is preferred over resection. Also the decision for management
may be changed according to patients well. Surgical resection 1- and 2-year survival rates were better than those treated
with RFA.

Key words: Hepatocellular carcinoma; liver resection; radiofrequency ablation

Address for correspondence:
Dr. Wael Mansy, Department of General Surgery, Faculty of Medicine, Zagazig University,
Zagazig 44519, Egypt. E-mail: drwaelmansy@hotmail.com
Received: 27-06-2015, Accepted: 26-10-2015

INTRODUCTION Radiofrequency ablation (RFA) is recommended for HCC
nodules with a maximum diameter of 3 cm in patients
Hepatic resection (HR) forms part of the conventional with no more than three tumors that are contraindicated
treatment for patients with hepatocellular carcinoma for surgery. [4]
(HCC). Size, site, number of tumors, vascular and extra-
[1]
hepatic involvement as well as liver function respresent METHODS
some aspects that prompt surgical resection difficulties.
Accordingly, the majority of primary liver cancers are not The patients were diagnosed through history taking,
suitable for curative resection at the time of diagnosis.
[2,3]
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DOI: How to cite this article: Mansy W, Mohammed M, Saber S. Surgical
10.4103/2394-5079.169642 resection or radiofrequency ablation in the management of hepatocellular
carcinoma: single center experience. Hepatoma Res 2016;2:92-7.

92 © 2016 Hepatoma Research | Published by OAE Publishing Inc.