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Anugwom et al. Hepatoma Res 2022;8:7  https://dx.doi.org/10.20517/2394-5079.2021.123  Page 11 of 13

                   systematic review. World J Gastroenterol 2015;21:11185-98.  DOI  PubMed  PMC
               13.      Bodzin AS, Lunsford KE, Markovic D, Harlander-Locke MP, Busuttil RW, Agopian VG. Predicting mortality in patients developing
                   recurrent hepatocellular carcinoma after liver transplantation: impact of treatment modality and recurrence characteristics. Ann Surg
                   2017;266:118-25.  DOI  PubMed
               14.      Guerrini GP, Berretta M, Tarantino G, et al. Multimodal oncological approach in patients affected by recurrent hepatocellular
                   carcinoma after liver transplantation. Eur Rev Med Pharmacol Sci 2017;21:3421-35.  PubMed
               15.      Couzin J. Cancer immunotherapy. Select T cells, given space, shrink tumors. Science 2002;297:1973.  DOI  PubMed
               16.      Mariotto AB, Yabroff KR, Shao Y, Feuer EJ, Brown ML. Projections of the cost of cancer care in the United States: 2010-2020. J Natl
                   Cancer Inst 2011;103:117-28.  DOI  PubMed  PMC
               17.      Cheng A, Kang Y, Chen Z, et al. Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular
                   carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol 2009;10:25-34.  DOI  PubMed
               18.      Llovet JM, Ricci S, Mazzaferro V, et al; SHARP Investigators Study Group. Sorafenib in advanced hepatocellular carcinoma. N Engl J
                   Med 2008;359:378-90.  DOI
               19.      Lué A, Serrano MT, Bustamante FJ, et al. Neutrophil-to-lymphocyte ratio predicts survival in European patients with hepatocellular
                   carcinoma administered sorafenib. Oncotarget 2017;8:103077-86.  DOI  PubMed  PMC
               20.      Sultan A, Anugwom CM, Wondifraw Z, Braimoh GA, Bane A, Debes JD. Single center analysis of therapy and outcomes of
                   hepatocellular carcinoma in Sub-Saharan Africa. Expert Rev Gastroenterol Hepatol 2020;14:1007-11.  DOI  PubMed  PMC
               21.      Wilhelm SM, Carter C, Tang L, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK
                   pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 2004;64:7099-109.  DOI  PubMed
               22.      Bruix J, Qin S, Merle P, et al. Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment
                   (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet 2017;389:56-66.  DOI  PubMed
               23.      Abou-Alfa GK, Meyer T, Cheng AL, et al. Cabozantinib in patients with advanced and progressing hepatocellular carcinoma. N Engl J
                   Med 2018;379:54-63.  DOI  PubMed  PMC
               24.      Kudo M, Finn RS, Qin S, et al. Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular
                   carcinoma: a randomised phase 3 non-inferiority trial. Lancet 2018;391:1163-73.  DOI  PubMed
               25.      Zhu AX, Park JO, Ryoo B, et al. Ramucirumab versus placebo as second-line treatment in patients with advanced hepatocellular
                   carcinoma following first-line therapy with sorafenib (REACH): a randomised, double-blind, multicentre, phase 3 trial. Lancet Oncol
                   2015;16:859-70.  DOI  PubMed
               26.      Yoong KF, McNab G, Hübscher SG, Adams DH. Vascular adhesion protein-1 and ICAM-1 support the adhesion of tumor-infiltrating
                   lymphocytes to tumor endothelium in human hepatocellular carcinoma. J Immunol 1998;160:3978-88.  PubMed
               27.      Hui E. Immune checkpoint inhibitors. J Cell Biol 2019;218:740-1.  DOI  PubMed  PMC
               28.      Chen L, Flies DB. Molecular mechanisms of T cell co-stimulation and co-inhibition. Nat Rev Immunol 2013;13:227-42.  DOI  PubMed
                   PMC
               29.      Gutierrez C, McEvoy C, Reynolds D, Nates JL. Toxicity of immunotherapeutic agents. Crit Care Clin 2021;37:605-24.  DOI  PubMed
               30.      El-khoueiry AB, Sangro B, Yau T, et al. Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-
                   label, non-comparative, phase 1/2 dose escalation and expansion trial. Lancet 2017;389:2492-502.  DOI  PubMed  PMC
               31.      Finn RS, Ryoo BY, Merle P, et al; KEYNOTE-240 investigators. Pembrolizumab as second-line therapy in patients with advanced
                   hepatocellular carcinoma in KEYNOTE-240: a randomized, double-blind, phase III trial. J Clin Oncol 2020;38:193-202.  DOI
                   PubMed
               32.      Yau T, Park J, Finn R, et al. CheckMate 459: A randomized, multi-center phase III study of nivolumab (NIVO) vs sorafenib (SOR) as
                   first-line (1L) treatment in patients (pts) with advanced hepatocellular carcinoma (aHCC). Ann Oncol 2019;30:v874-5.  DOI
               33.      Finn RS, Qin S, Ikeda M, et al; IMbrave150 Investigators. Atezolizumab plus bevacizumab in unresectable hepatocellular carcinoma.
                   N Engl J Med 2020;382:1894-905.  DOI  PubMed
               34.      Ren Z, Fan J, Xu J, et al. LBA2 Sintilimab plus bevacizumab biosimilar vs sorafenib as first-line treatment for advanced hepatocellular
                   carcinoma (ORIENT-32)2. Ann Oncol 2020;31:S1287.  DOI
               35.      Sangro B, Sarobe P, Hervás-Stubbs S, Melero I. Advances in immunotherapy for hepatocellular carcinoma. Nat Rev Gastroenterol
                   Hepatol 2021;18:525-43.  DOI  PubMed  PMC
               36.      Huang H, Lu Y, Zhou T, Gu G, Xia Q. Innate immune cells in immune tolerance after liver transplantation. Front Immunol
                   2018;9:2401.  DOI  PubMed  PMC
               37.      Thomson AW, Knolle PA. Antigen-presenting cell function in the tolerogenic liver environment. Nat Rev Immunol 2010;10:753-66.
                   DOI  PubMed
               38.      de la Garza RG, Sarobe P, Merino J, et al. Trial of complete weaning from immunosuppression for liver transplant recipients: factors
                   predictive of tolerance. Liver Transpl 2013;19:937-44.  DOI  PubMed
               39.      Feng S, Bucuvalas JC, Mazariegos GV, et al. Efficacy and safety of immunosuppression withdrawal in pediatric liver transplant
                   recipients: moving toward personalized management. Hepatology 2021;73:1985-2004.  DOI  PubMed
               40.      Starzl TE, Marchioro TL, Vonkaulla KN, Hermann G, Brittain RS, Waddell WR. Homotransplantation of the liver in humans. Surg
                   Gynecol Obstet 1963;117:659-76.  PubMed  PMC
               41.      Starzl TE, Marchioro TL, Waddell WR. The reversal of rejection in human renal homografts with subsequent development of
                   homograft tolerance. Surg Gynecol Obstet 1963;117:385-95.  PubMed  PMC
               42.      Eason JD, Loss GE, Blazek J, Nair S, Mason AL. Steroid-free liver transplantation using rabbit antithymocyte globulin induction:
                   results of a prospective randomized trial. Liver Transpl 2001;7:693-7.  DOI  PubMed
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