Page 25 - Read Online
P. 25

14.  Klaunig  JE,  Kamendulis  LM.  The  role  of  oxidative  stress  in   carcinogenic and chemopreventive agents. Front Biosci (Schol Ed)
              carcinogenesis. Annu Rev Pharmacol Toxicol 2004;44:239-67.  2009;1:45-60.
          15.  Pang  R, Tse  E,  Poon  RT.  Molecular  pathways  in  hepatocellular   35.  Shishodia S, Amin HM, Lai R, Aggarwal BB. Curcumin (diferuloylmethane)
              carcinoma. Cancer Lett 2006;240:157-69.             inhibits  constitutive  NF-kappaB  activation,  induces  G1/S  arrest,
          16.  Wong CM, Ng IO. Molecular pathogenesis of hepatocellular carcinoma.   suppresses proliferation, and induces apoptosis in mantle cell lymphoma.
              Liver Int 2008;28:160-74.                           Biochem Pharmacol 2005;70:700-13.
          17.  Frau M, Biasi F, Feo F, Pascale RM. Prognostic markers and putative   36.  Kamat AM, Sethi G, Aggarwal BB. Curcumin potentiates the apoptotic
              therapeutic targets for hepatocellular carcinoma.  Mol Aspects Med   effects of chemotherapeutic agents and cytokines through down-regulation
              2010;31:179-93.                                     of nuclear factor-kappaB and nuclear factor-kappaB-regulated gene
          18.  Darvesh AS, Aggarwal BB, Bishayee A. Curcumin and liver cancer: a   products in IFN-alpha-sensitive and IFN-alpha-resistant human bladder
              review. Curr Pharm Biotechnol 2012;13:218-28.       cancer cells. Mol Cancer Ther 2007;6:1022-30.
          19.  Lee JH, Kim HY, Kim YJ, Yoon JH, Chung JW, Lee HS. Barcelona Clinic   37.  Li  L, Aggarwal  BB,  Shishodia  S, Abbruzzese  J,  Kurzrock  R.
              Liver Cancer staging system and survival of untreated hepatocellular   Nuclear  factor-kappaB  and  IkappaB  kinase  are  constitutively
              carcinoma in a hepatitis B virus endemic area. J Gastroenterol Hepatol   active  in  human  pancreatic  cells,  and  their  down-regulation  by
              2015;30:696-705.                                    curcumin (diferuloylmethane) is associated with the suppression of
          20.  Takayasu K, Muramatsu Y, Moriyama N, Hasegawa H, Makuuchi M,   proliferation and the induction of apoptosis. Cancer 2004;101:2351-62.
              Okazaki N, Hirohashi S, Tsugane S. Clinical and radiologic assessments   38.  Shakibaei M, Schulze-Tanzil G, John T, Mobasheri A. Curcumin protects
              of the results of hepatectomy for small hepatocellular carcinoma and   human chondrocytes from IL-l1beta-induced inhibition of collagen
              therapeutic arterial embolization for postoperative recurrence. Cancer   type II and beta1-integrin expression and activation of caspase-3: an
              1989;64:1848-52.                                    immunomorphological study. Ann Anat 2005;187:487-97.
          21.  Sato M, Watanabe Y, Ueda S, Iseki S, Abe Y, Sato N, Kimura S, Okubo K,   39.  Skommer J, Wlodkowic D, Pelkonen J. Gene-expression profi ling during
              Onji M. Microwave coagulation therapy for hepatocellular carcinoma.   curcumin-induced apoptosis reveals downregulation of CXCR4. Exp
              Gastroenterology 1996;110:1507-14.                  Hematol 2007;35:84-95.
          22.  Llovet JM, Burroughs A, Bruix J. Hepatocellular carcinoma. Lancet   40.  Wang S, Yu S, Shi W, Ge L, Yu X, Fan J, Zhang J. Curcumin inhibits
              2003;362:1907-17.                                   the migration and invasion of mouse hepatoma Hca-F cells through
          23.  Mazzaferro V, Regalia E, Doci R, Andreola S, Pulvirenti A, Bozzetti F,   down-regulating caveolin-1 expression and epidermal growth factor
              Montalto F, Ammatuna M, Morabito A, Gennari L. Liver transplantation   receptor signaling. IUBMB Life 2011;63:775-82.
              for the treatment of small hepatocellular carcinomas in patients with   41.  Lin  LI,  Ke YF,  Ko YC,  Lin  JK.  Curcumin  inhibits  SK-Hep-1
              cirrhosis. N Engl J Med 1996;334:693-9.             hepatocellular carcinoma cell invasion in vitro and suppresses matrix
          24.  Llovet JM, Ricci S, Mazzaferro V, Hilgard P, Gane E, Blanc JF, de   metalloproteinase-9 secretion. Oncology 1998;55:349-53.
              Oliveira AC, Santoro A, Raoul JL, Forner A, Schwartz M, Porta C,   42.  Chiablaem K, Lirdprapamongkol K, Keeratichamroen S, Surarit R,
              Zeuzem S, Bolondi L, Greten TF, Galle PR, Seitz JF, Borbath I,   Svasti J. Curcumin suppresses vasculogenic mimicry capacity of
              Häussinger D, Giannaris T, Shan M, Moscovici M, Voliotis D, Bruix J;   hepatocellular carcinoma cells through STAT3 and PI3K/AKT inhibition.
              SHARP Investigators Study Group. Sorafenib in advanced hepatocellular   Anti-cancer Res 2014;34:1857-64.
              carcinoma. N Engl J Med 2008;359:378-90.        43.  Shoji M, Nakagawa K, Watanabe A, Tsuduki T, Yamada T, Kuwahara S,
          25.  Je Y, Schutz FA, Choueiri TK. Risk of bleeding with vascular endothelial   Kimura F, Miyazawa T. Comparison of the effects of curcumin and
              growth factor receptor tyrosine-kinase inhibitors sunitinib and sorafenib:   curcumin glucuronide in human hepatocellular carcinoma HepG2 cells.
              a systematic review and meta-analysis of clinical trials. Lancet Oncol   Food Chem 2014;151:126-32.
              2009;10:967-74.                                 44.  Bandyopadhyay D. Farmer to pharmacist: curcumin as an anti-invasive
          26.  Lu  SC. Where  are  we  in  the  chemoprevention  of  hepatocellular   and anti-metastatic agent for the treatment of cancer.  Front Chem
              carcinoma? Hepatology 2010;51:734-6.                2014;2:113.
          27.  Dai XZ, Yin HT, Sun LF, Hu X, Zhou C, Zhou Y, Zhang W, Huang XE,   45.  Bishayee A, Politis T, Darvesh AS. Resveratrol in the chemoprevention
              Li XC. Potential therapeutic effi cacy of curcumin in liver cancer. Asian   and  treatment  of  hepatocellular  carcinoma.  Cancer Treat Rev
              Pac J Cancer Prev 2013;14:3855-9.                   2010;36:43-53.
          28.  Lin W, Zhao J, Cao Z, Zhuang Q, Zheng L, Cai Q, Chen D, Wang L,   46.  Baur JA, Sinclair DA. Therapeutic potential of resveratrol: the in vivo
              Hong Z, Peng J. Livistona chinensis seed suppresses hepatocellular   evidence. Nat Rev Drug Discov 2006;5:493-506.
              carcinoma growth through promotion of mitochondrial-dependent   47.  Udenigwe CC, Ramprasath VR, Aluko RE, Jones PJ. Potential of
              apoptosis. Oncol Rep 2013;29:1859-66.               resveratrol in anti-cancer and anti-infl ammatory therapy. Nutr Rev
          29.  Xia JF, Gao JJ, Inagaki Y, Kokudo N, Nakata M, Tang W. Flavonoids as   2008;66:445-54.
              potential anti-hepatocellular carcinoma agents: recent approaches using   48.  Saiko P, Szakmary A, Jaeger W, Szekeres T. Resveratrol and its analogs:
              HepG2 cell line. Drug Discov Ther 2013;7:1-8.       defense against cancer, coronary disease and neurodegenerative maladies
          30.  Aggarwal BB, Harikumar KB. Potential therapeutic effects of curcumin,   or just a fad? Mutat Res 2008;658:68-94.
              the anti-infl ammatory agent, against neurodegenerative, cardiovascular,   49.  Shankar S, Singh G, Srivastava RK. Chemoprevention by resveratrol:
              pulmonary, metabolic, autoimmune and neoplastic diseases.  Int J   molecular  mechanisms  and  therapeutic  potential.  Front Biosci
              Biochem Cell Biol 2009;41:40-59.                    2007;12:4839-54.
          31.  Sugiyama Y, Kawakishi S, Osawa T. Involvement of the beta-diketone   50.  Das S, Das DK. Anti-infl ammatory responses of resveratrol. Infl amm
              moiety in the anti-oxidative mechanism of tetrahydrocurcumin. Biochem   Allergy Drug Targets 2007;6:168-73.
              Pharmacol 1996;52:519-25.                       51.  Rubiolo JA, Mithieux G, Vega FV. Resveratrol protects primary rat
          32.  Singh S, Aggarwal BB. Activation of transcription factor NF-kappa B is   hepatocytes against oxidative stress damage: activation of the  Nrf2
              suppressed by curcumin (diferuloylmethane) [corrected]. J Biol Chem   transcription factor and augmented activities of anti-oxidant enzymes.
              1995;270:24995-5000.                                Eur J Pharmacol 2008;591:66-72.
          33.  Libby P. Infl ammatory mechanisms: the molecular basis of infl ammation   52.  Delmas D, Jannin B, Cherkaoui Malki M, Latruffe N. Inhibitory effect
              and disease. Nutr Rev 2007;65:S140-6.               of resveratrol on the proliferation of human and rat hepatic derived cell
          34.  Ralhan R, Pandey MK, Aggarwal BB. Nuclear factor-kappa B links   lines. Oncol Rep 2000;7:847-52.



               Hepatoma Research | Volume 1 | Issue 3 | October 15, 2015                                    123
   20   21   22   23   24   25   26   27   28   29   30