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Kanmaniraja et al. Hepatoma Res 2020;6:51 Hepatoma Research
DOI: 10.20517/2394-5079.2020.46

Review Open Access

Liver imaging reporting and data system and CT/MRI
diagnosis of hepatocellular carcinoma

Devaraju Kanmaniraja, Victoria Chernyak

Radiology, Montefiore Medical Center, The Bronx, New York, NY 10467, USA.
Correspondence to: Prof. Victoria Chernyak, Radiology, Montefiore Medical Center, The Bronx, 111 East 210th St Bronx, New
York, NY 10467, USA. E-mail: vichka17@hotmail.com

How to cite this article: Kanmaniraja D, Chernyak V. Liver imaging reporting and data system and CT/MRI diagnosis of
hepatocellular carcinoma. Hepatoma Res 2020;6:51. http://dx.doi.org/10.20517/2394-5079.2020.46

Received: 29 Apr 2020 First Decision: 11 Jun 2020 Revised: 21 Jun 2020 Accepted: 24 Jun 2020 Published: 15 Aug 2020

Academic Editor: Yuko Kono Copy Editor: Cai-Hong Wang Production Editor: Jing Yu

Abstract
The Liver Imaging Reporting and Data System (LI-RADS) is a comprehensive and robust system which provides
Received: First Decision: Revised: Accepted: Published: an algorithmic approach to stratify the probability of hepatocellular carcinoma (HCC) for each observation found
in patients at risk for HCC. LI-RADS uses a standardized terminology and approach to improve communication
Science Editor: Copy Editor: Production Editor: Jing Yu between the radiologist and clinicians. LI-RADS version 2018 is noteworthy for its adoption by the American
Association for the Study of Liver Disease into its HCC practice guidance. This manuscript provides an overview
of the history of LI-RADS, reviews the Computed tomography/magnetic resonance imaging diagnostic algorithm,
highlights the key diagnostic criteria for each category, and discusses the advantage of incorporating LI-RADS in
clinical practice.

Keywords: Liver Imaging Reporting and Data System, hepatocellular carcinoma, cirrhosis, hepatocellular carcinoma
diagnosis

INTRODUCTION
[1]
Hepatocellular cancer (HCC) is the most common primary malignancy of the liver . It is the fifth most
[1,2]
common cancer in the world and fourth leading cause of cancer mortality . The incidence of HCC in the
[3,4]
United States has been rapidly rising over the last 20 years and predicted to increase until 2030 . Imaging
plays a critical role in the management of HCC, as the diagnosis of HCC is usually made non-invasively in
the appropriate at-risk patient population, based on imaging features alone without the need of pathologic

© The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0
International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use,
sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long
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