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Page 8 of 22 Guerriero et al. Hepatoma Res 2019;5:6 I http://dx.doi.org/10.20517/2394-5079.2018.108

miR-122-5p Up Plasma Single Diagnosis LC vs. HL 20 vs. 22 N/A N/A N/A [43]
miR-122-5p Up Plasma Single Diagnosis HCC vs. HL + LC 7 vs. 14 + 21 N/A N/A N/A [51]
miR-122-5p Up Serum Single Diagnosis HCC vs. LC 24 vs. 14 N/A N/A N/A [51]
miR-122a Down Serum Single Diagnosis HCC vs. HL 85 vs. 85 70.6 67.1 0.71 [130]
miR-122a Down Serum Single + AFP Diagnosis HCC vs. HL 85 vs. 85 87.1 98.8 0.94 [130]
miR-1247-3p Up Serum Single Diagnosis HCC vs. HL 110 vs. 25 N/A N/A N/A [131]
miR-125a-5p Down Serum Single Diagnosis HCC vs. HL + CHB 120 vs. 164 + N/A N/A N/A [76]
91
miR-125b Down Plasma Single Diagnosis HCC vs. CHB 64 vs. 63 93.8 85.7 0.96 [58]
miR-125b Down Plasma Single Diagnosis HCC vs. HL 64 vs. 56 85.9 78.6 0.89 [58]
miR-125b Down Plasma Single Diagnosis HCC vs. LC 64 vs. 59 89.1 88.1 0.96 [58]
miR-125b, miR- Down Serum Multiple + Diagnosis HCC vs. HL 90 vs. 60 N/A N/A 0.87 [50]
223, miR-27a, AFP
and miR-26a
miR-125b, miR- Down Serum Multiple + Diagnosis HCC vs. HL 90 vs. 60 80.0 87.2 N/A [50]
27a AFP
miR-125b-5p Up Plasma Single Diagnosis CHB vs. HL 20 vs. 24 N/A N/A N/A [43]
miR-125b-5p Up Plasma Single Diagnosis HCC vs. HL 20 vs. 28 N/A N/A N/A [43]
miR-125b-5p Up Plasma Single Diagnosis LC vs. HL 20 vs. 22 N/A N/A N/A [43]
miR-143 Down Serum Single Diagnosis HCC vs. HL 131 vs. 122 80.3 82.4 0.83 [132]
miR-145 Down Serum Single Diagnosis HCC vs. CHB 85 vs. 50 88.2 78.0 0.85 [133]
miR-148a Down Serum Single Diagnosis HCC vs. HL + BLD 76 vs. 55 + 62 67.7 59.2 0.67 [71]
miR-148a, miR- Down Serum Multiple Diagnosis HCC vs. BLD 76 vs. 62 96.1 91.9 0.94 [71]
148b, miR-152
miR-15b Up Serum Single Diagnosis HCC vs. HL + CHB 57 vs. 30 + 29 98.3 15.3 0.49 [124]
miR-15b, miR- Up Serum Multiple Diagnosis HCC vs. HL + CHB 57 vs. 30 + 29 98.3 91.5 0.98 [124]
130b
miR-16 Down Serum Single + AFP Diagnosis HCC vs. HL + CLD 105 vs. 71 + 92.4 78.5 N/A [134]
107
miR-16, miR- Serum Multiple Diagnosis HCC vs. HL + CLD 105 vs. 71 + N/A N/A N/A [134]
195, miR-199a 107
miR-18, miR- Up Exosomes Single Diagnosis HCC vs. LC 20 vs. 20 N/A N/A N/A [127]
221, miR-222,
miR-224
miR-18, miR- Up Exosomes Single Diagnosis HCC vs. CHB + LC 20 vs. 20 + 20 N/A N/A N/A [127]
221, miR-222,
miR-224
miR-182 Up Serum Single + AFP Diagnosis HCC vs. HL + BLD 103 vs. 40 + 82.5 94.7 [135]
95
miR-182 Up Serum Single Diagnosis HCC vs. HL + BLD 103 vs. 40 + 78.6 91.6 0.91 [135]
95
miR-182, miR- Serum Multiple + Diagnosis HCC vs. HL + BLD 103 vs. 40 + 93.2 95.8 N/A [135]
331-3p AFP 95
miR-192-5p Up Serum Single Diagnosis HCC vs. HL + LC 74 vs. 60 + 43 N/A N/A 0.69 [125]
(T)
miR-192-5p Up Serum Single Diagnosis HCC vs. HL (T) 50 vs. 50 N/A N/A N/A [125]
and miR-29a-
3p
miR-192-5p Up Serum Single Diagnosis HCC vs. HL (V) 100 vs. 70 N/A N/A N/A [125]
and miR-29a-
3p
miR-199a Down Serum Single Diagnosis HCC vs. CH 23 vs. 17 54.5 100 0.85 [136]
miR-21 Up Serum Single Diagnosis HCC vs. CH 23 vs. 17 100 82.1 0.94 [136]
miR-21 Up Serum Single Diagnosis CHC vs. HL 62 vs. 19 87.1 73.7 0.83 [137]
miR-21 Up Serum Single Diagnosis HCC vs. HL 29 vs. 19 N/A N/A N/A [137]
miR-21 Up Serum Single Diagnosis HCC vs. LC (V) 175 vs. 78 80.8 72.9 0.81 [59]
miR-21 Up Serum Single Diagnosis HCC vs. CHB (V) 175 vs. 64 76.9 85.7 0.79 [59]
miR-21 Up Serum Single Diagnosis HCC vs. HL (T) 40 vs. 40 [59]
miR-21 Up Serum Single Diagnosis HCC vs. HL + CHB 175 vs. 136 + 82.1 83.9 0.85 [59]
+ LC (V) 64 + 78
miR-21 Up Single Diagnosis HCC vs. HL + CHB 3423 vs. 1887 86.6 79.5 0.88 [128]
+ 2403
miR-21 Down Serum Single Diagnosis HCC vs. HL 70 vs. 34 N/A N/A N/A [45]
miR-21 Up Plasma Single + AFP Diagnosis HCC vs. HL + CH 127 vs. 50 + 90.0 92.9 0.82 [48]
30
miR-21 Up Plasma Single Diagnosis HCC vs. HL + CH 126 vs. 50 + 61.1 83.3 0.77 [48]
30