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Page 10 of 14 Xu et al. Cancer Drug Resist 2024;7:13 https://dx.doi.org/10.20517/cdr.2023.141

circRNA still focuses on sponge function, while the mechanism and function of circRNA as a translation
template or binding protein are still relatively unknown. This review briefly explained the biosynthetic
mechanism and functions of circRNA. We also described several major biological events in which circRNA
is involved for the progression of TNBC, and summarized current information on circRNAs in relation to
the survival prognosis of TNBC. This article did not explain how circRNA is degraded or about its
regulatory relationship with parental genes. Additionally, the summarized biological events are not
comprehensive, but representative of selected hot topics at present.

DECLARATIONS
Authors’ contributions
Writing-original draft: Xu A
Writing-review and editing: Zhu L
Collect some literature: Yao C
Providing review ideas and guidance: Zhou W, Guan Z

Availability of data and materials
Not applicable.

Financial support and sponsorship
This research was supported by the Guangdong Basic and Applied Basic Research Foundation (Nos.
2021B1515120053, 2020A1515010185).

Conflict of interests
All authors declared that there are no conflicts of interest.

Ethical approval and consent to participate
Not applicable.

Consent for publication
Not applicable.

Copyright
© The Author(s) 2024.

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