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Cheng et al. Cancer Drug Resist. 2025;8:46 Page 15 of 28
Figure 5. (A) Schematic illustration of the injectable hydrogel and its role in T cell recruitment, reversal of T cell exhaustion, and MHC
I-regulated immune escape in cancer immunotherapy; (B) In vivo inhibitory effects of the hydrogel on primary tumor and abscopal tumors.
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* P < 0.05, P < 0.01, P < 0.001 [reproduced with permission from Zhang et al. (2022) [150] . Copyright 2022 John Wiley and Sons]. MHC I:
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Major histocompatibility complex class I.
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